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MRI引导下乳腺病变活检后的病变特征、组织病理学结果及随访情况

Lesion characteristics, histopathologic results, and follow-up of breast lesions after MRI-guided biopsy.

作者信息

Taşkın Füsun, Soyder Aykut, Tanyeri Ahmet, Öztürk Veli Süha, Ünsal Alparslan

机构信息

Deparment of Radiology, Adnan Menderes University School of Medicine, Aydın, Turkey.

出版信息

Diagn Interv Radiol. 2017 Sep-Oct;23(5):333-338. doi: 10.5152/dir.2017.17004.

DOI:10.5152/dir.2017.17004
PMID:28830847
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5602356/
Abstract

PURPOSE

We aimed to assess the effectiveness of magnetic resonance imaging (MRI)-guided vacuum-assisted breast biopsy (VABB), evaluate and compare the characteristics and histopathologic findings of lesions, and overview the follow-up results of benign lesions.

METHODS

MRI findings and histopathologic results of breast lesions biopsied by MRI-guided VABB between 2013 and 2016 were retrospectively analyzed. MRI findings closely related with malignancy were investigated in particular. Follow-up results of benign lesions were evaluated.

RESULTS

MRI-guided VABB was applied to 116 lesions of 112 women. Of the lesions, 75 (65%) were benign, while 41 (35%) were malignant. Segmental (94%), clustered (89%), and clustered ring (67%) non-mass-like enhancement patterns were found to be more related with malignancy. False-negative rate of MRI-guided VABB was 12%, underestimation rate was 21%. One of the 54 followed-up benign lesions had a malignant result.

CONCLUSION

MRI-guided VABB is a reliable method for the diagnosis of breast lesions that are positive only on MRI. Follow-up results show that cancer detection rate is low for radio-pathologically concordant lesions. Further multicenter studies with larger patient population are needed to elucidate these results.

摘要

目的

我们旨在评估磁共振成像(MRI)引导下真空辅助乳腺活检(VABB)的有效性,评估并比较病变的特征和组织病理学发现,以及概述良性病变的随访结果。

方法

回顾性分析2013年至2016年间通过MRI引导VABB进行活检的乳腺病变的MRI表现和组织病理学结果。特别研究了与恶性肿瘤密切相关的MRI表现。评估良性病变的随访结果。

结果

对112名女性的116个病变进行了MRI引导下的VABB。其中,75个(65%)病变为良性,41个(35%)为恶性。发现节段性(94%)、簇状(89%)和簇状环状(67%)非肿块样强化模式与恶性肿瘤的相关性更高。MRI引导下VABB的假阴性率为12%,低估率为21%。54个随访的良性病变中有1个出现恶性结果。

结论

MRI引导下的VABB是诊断仅在MRI上呈阳性的乳腺病变的可靠方法。随访结果表明,对于放射病理学一致的病变,癌症检出率较低。需要进一步开展更大规模患者群体的多中心研究来阐明这些结果。

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本文引用的文献

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Underestimation Rate at MR Imaging-guided Vacuum-assisted Breast Biopsy: A Multi-Institutional Retrospective Study of 1509 Breast Biopsies.MR 成像引导下真空辅助乳腺活检的低估率:1509 例乳腺活检的多机构回顾性研究。
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MR-guided vacuum-assisted breast biopsy of MRI-only lesions: a single center experience.磁共振引导下仅磁共振成像(MRI)发现的乳腺病变的真空辅助活检:单中心经验
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Recommendations for excision following core needle biopsy of the breast: a contemporary evaluation of the literature.乳腺粗针活检后切除的建议:对文献的当代评估
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Lesions with unclear malignant potential (B3) after minimally invasive breast biopsy: evaluation of vacuum biopsies performed in Switzerland and recommended further management.微创乳腺活检后具有不确定恶性潜能的病变(B3):对瑞士进行的真空活检的评估及推荐的进一步管理措施
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