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Successful non-directed living liver donor transplant for an infant with biliary atresia during the COVID-19 pandemic.COVID-19 大流行期间成功进行非定向活体肝移植治疗婴儿胆道闭锁。
Pediatr Transplant. 2020 Dec;24(8):e13816. doi: 10.1111/petr.13816. Epub 2020 Aug 14.
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Living Related Liver Transplantation for Biliary Atresia in the Last 5 years: Experience from the First Liver Transplant Program in India.过去5年印度首例肝移植项目中活体亲属肝移植治疗胆道闭锁的经验
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Lessons Learned From Review of a Single Center Experience With 500 Consecutive Liver Transplants in a Region With Insufficient Deceased-Donor Support.在一个脑死亡供体支持不足地区,对连续500例肝移植单中心经验回顾所获的经验教训
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[Postoperative intensive care of biliary atresia patients treated with living donor liver transplantation].[活体供肝肝移植治疗胆道闭锁患者的术后重症监护]
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Effects of recipient size and allograft type on pediatric liver transplantation for biliary atresia.受体大小和同种异体移植物类型对小儿胆道闭锁肝移植的影响。
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Liver Donation and Transplantation in Poland: Numbers, Indicators, and Trends.波兰的肝脏捐赠与移植:数量、指标及趋势
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本文引用的文献

1
Organ donation during the coronavirus pandemic: an evolving saga in uncharted waters.新冠疫情期间的器官捐赠:未知水域中的一段不断演变的故事。
Transpl Int. 2020 Jul;33(7):826-827. doi: 10.1111/tri.13614. Epub 2020 Apr 29.
2
COVID-19 in long-term liver transplant patients: preliminary experience from an Italian transplant centre in Lombardy.长期肝移植患者中的新型冠状病毒肺炎:来自意大利伦巴第地区一家移植中心的初步经验。
Lancet Gastroenterol Hepatol. 2020 Jun;5(6):532-533. doi: 10.1016/S2468-1253(20)30116-3. Epub 2020 Apr 9.
3
Coronaviruses and Immunosuppressed Patients: The Facts During the Third Epidemic.冠状病毒与免疫抑制患者:第三次疫情期间的实际情况
Liver Transpl. 2020 Jun;26(6):832-834. doi: 10.1002/lt.25756. Epub 2020 Apr 24.
4
Superior Outcomes and Reduced Wait Times in Pediatric Recipients of Living Donor Liver Transplantation.活体供肝肝移植小儿受者的更佳预后及缩短等待时间
Transplant Direct. 2019 Feb 27;5(3):e430. doi: 10.1097/TXD.0000000000000865. eCollection 2019 Mar.
5
OPTN/SRTR 2017 Annual Data Report: Liver.OPTN/SRTR 2017 年度数据报告:肝脏。
Am J Transplant. 2019 Feb;19 Suppl 2:184-283. doi: 10.1111/ajt.15276.
6
Intrahepatic cystic lesions after hepatic portoenterostomy for biliary atresia with bile lake and dilated bile ducts.肝门空肠吻合术后肝内囊性病变,伴胆汁湖和胆管扩张,用于治疗胆道闭锁。
J Pediatr Gastroenterol Nutr. 2007 Jan;44(1):104-7. doi: 10.1097/01.mpg.0000237930.45846.ae.

COVID-19 大流行期间成功进行非定向活体肝移植治疗婴儿胆道闭锁。

Successful non-directed living liver donor transplant for an infant with biliary atresia during the COVID-19 pandemic.

机构信息

Section of Gastroenterology, Hepatology and Nutrition and the Digestive Health Institute, University of Colorado School of Medicine, Anschutz Medical Campus & Children's Hospital Colorado, Aurora, Colorado, USA.

Division of Transplant Surgery, University of Colorado School of Medicine, Anschutz Medical Campus & Children's Hospital Colorado, Aurora, Colorado, USA.

出版信息

Pediatr Transplant. 2020 Dec;24(8):e13816. doi: 10.1111/petr.13816. Epub 2020 Aug 14.

DOI:10.1111/petr.13816
PMID:33460202
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7988506/
Abstract

Amidst the coronavirus (COVID-19) pandemic, the American Society for Transplant Surgeons has recommended that only urgent liver transplant with deceased donors should occur. However, young pediatric candidates rely on living donors for lifesaving transplant. We present a case of non-directed left lateral lobe living liver donor transplant for a 7-month-old child with biliary atresia experiencing repeated life-threatening episodes of sepsis and cholangitis from infected bile lakes. Using careful preoperative planning among the entire multidisciplinary team, paying meticulous attention to infection control pre- and post-operatively, and taking advantage of robust telehealth technology both in and out of the hospital, a successful transplant was achieved. Amidst the COVID pandemic, non-directed liver transplantation can be safely achieved for pediatric recipients.

摘要

在冠状病毒(COVID-19)大流行期间,美国移植外科学会建议仅进行紧急的已故供体肝移植。然而,年轻的儿科患者需要依靠活体供者进行挽救生命的移植。我们报告了一例非定向左外侧叶活体肝移植的病例,供者为一名 7 个月大的胆道闭锁婴儿,该患儿因感染性胆汁湖反复发作威胁生命的败血症和胆管炎。整个多学科团队进行了仔细的术前规划,术前和术后都非常注意感染控制,并充分利用医院内外强大的远程医疗技术,最终成功完成了移植。在 COVID 大流行期间,非定向肝移植可以安全地为儿科受者进行。