头颈部癌症患者颈部放疗对颈动脉多普勒超声结果的影响。
Effects of Neck Radiation on Result of Doppler Sonography of Carotid Arteries in Head and Neck Cancer Patients.
机构信息
Department of radiation oncology, Isfahan university of medical sciences, Isfahan, Iran.
Department of radiology, cancer prevention research center, school of medicine, Isfahan niversity of medical sciences, Isfahan, Iran.
出版信息
J Stroke Cerebrovasc Dis. 2021 Apr;30(4):105607. doi: 10.1016/j.jstrokecerebrovasdis.2021.105607. Epub 2021 Jan 15.
PURPOSE
The aim of this study was to assess the effects of neck radiation on the results of Doppler sonography of carotid arteries in head and neck cancer patients.
METHODS
In this prospective, cross-sectional study, 25 consecutive patients with head and neck cancers were assessed for carotid artery stenosis (CAS) by carotid color Doppler sonography before external radiotherapy and six months after external radiotherapy. Main outcome measures were peak systolic velocity (PSVs), end-diastolic velocities (EDVs) of the internal carotid artery (ICA), ICA/common carotid (CCA) ratios, and degree of stenosis.
RESULTS
The age of the enrolled patients at the initiation of radiotherapy was 57.9±11.8 years (mean±SD; range, 43-91 years), and only 4 (16%) of the 25 patients were female. The findings showed significant changes in the plaque degree and stenosis degree, and plaque size before and after external radiotherapy (P<0.05). Changes in degree of stenosis were significantly correlated with age (p=0.021).
CONCLUSION
After neck irradiation changes in the carotid artery may occur and cause subsequent neurologic events.
目的
本研究旨在评估颈部放疗对头颈部癌症患者颈动脉多普勒超声结果的影响。
方法
在这项前瞻性、横断面研究中，25 例连续的头颈部癌症患者在接受外部放疗前和放疗后 6 个月进行颈动脉彩色多普勒超声检查，以评估颈动脉狭窄（CAS）的情况。主要观察指标为颈内动脉（ICA）收缩期峰值速度（PSV）、舒张末期速度（EDV）、ICA/颈总动脉（CCA）比值和狭窄程度。
结果
放疗开始时患者的年龄为 57.9±11.8 岁（均值±标准差；范围，43-91 岁），25 例患者中仅有 4 例（16%）为女性。放疗前后斑块程度和狭窄程度以及斑块大小的发现均有显著变化（P<0.05）。狭窄程度的变化与年龄显著相关（p=0.021）。
结论
颈部放疗后颈动脉可能会发生变化，并导致随后的神经事件。
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