Electrical and Electronic Engineering, School of Engineering, NUI Galway, University Road, Galway, Ireland; Human Movement Laboratory, CÚRAM Centre for Research in Medical Devices, NUI Galway, University Road, Galway, Ireland.
Human Movement Laboratory, CÚRAM Centre for Research in Medical Devices, NUI Galway, University Road, Galway, Ireland; Physiology, School of Medicine, NUI Galway, University Road, Galway, Ireland.
Med Eng Phys. 2021 Jan;87:73-81. doi: 10.1016/j.medengphy.2020.11.007. Epub 2020 Nov 17.
Due to possible sensory impairments in people with Parkinson's disease, several methodological aspects of electrical stimulation as a potential cueing method remain to be explored. This study aimed to investigate the applicability and tolerability of sensory and motor electrical stimulation in 10 people with Parkinson's disease. The study focused on assessing the electrical stimulation voltages and visual analogue scale discomfort scores at the electrical sensory, motor, discomfort, and pain thresholds. Results show that sensory electrical stimulation at the tibialis anterior, soleus, hamstrings, and quadriceps stimulation sites was applicable and tolerable for 6/10, 10/10, 9/10, and 10/10 participants, respectively. Furthermore, motor electrical stimulation at the tibialis anterior, soleus, hamstrings, and quadriceps stimulation sites were applicable and tolerable for 7/10, 7/10, 7/10, and 8/10 participants, respectively. Interestingly, the thresholds for the lower leg were higher than those of the upper leg. The data presented in this paper indicate that sensory and motor electrical stimulation is applicable and tolerable for cueing applications in people with Parkinson's disease. Sensory electrical stimulation was applicable and tolerable at the soleus and quadriceps sites. Motor electrical stimulation was not tolerable for two participants at any of the proposed stimulation sites. Therefore, future studies investigating motor electrical stimulation cueing, should apply it with caution in people with Parkinson's disease.
由于帕金森病患者可能存在感觉障碍，因此需要探索几种电刺激作为潜在提示方法的方法学方面。本研究旨在调查 10 名帕金森病患者中感觉和运动电刺激的适用性和耐受性。该研究重点评估了电刺激的感觉、运动、不适和疼痛阈值的电刺激电压和视觉模拟量表不适评分。结果表明，在前胫骨、比目鱼肌、腘绳肌和股四头肌刺激部位的感觉电刺激在 6/10、10/10、9/10 和 10/10 名参与者中分别具有适用性和耐受性。此外，在前胫骨、比目鱼肌、腘绳肌和股四头肌刺激部位的运动电刺激在 7/10、7/10、7/10 和 8/10 名参与者中分别具有适用性和耐受性。有趣的是，小腿的阈值高于大腿的阈值。本文提供的数据表明，感觉和运动电刺激适用于帕金森病患者的提示应用，并且具有可耐受性。感觉电刺激在前胫骨和股四头肌部位具有适用性和耐受性。在任何建议的刺激部位，运动电刺激对于两名参与者来说均不可耐受。因此，未来研究在调查运动电刺激提示时，应该在帕金森病患者中谨慎应用。
