Antiaggressive effect of adjunctive clonazepam in schizophrenia associated with seizure disorder.

A case of schizophrenia associated with complex partial seizure disorder and postictal violence, both refractory to conventional treatment, is presented. Adjunctive treatment with clonazepam resulted in the cessation of the seizures and of persistent, violent hallucinations. The theoretical implications for possible mechanisms underlying at least some types of aggressive behavior are discussed.