Gross R A, Herridge P
Neurology Service, Massachusetts General Hospital, Boston.
J Clin Psychiatry. 1988 Mar;49(3):119-20.
Secondary mania may be caused by metabolic derangements, intoxications, and/or structural lesions, as well as by epilepsy. The authors describe a maniclike illness in a 16-year-old girl in whom a right frontal arteriovenous malformation was discovered. The most effective medical therapy was a combination of lithium and carbamazepine. Ultimately, the malformation was resected, and since then the patient has done well without medication. The possibility is raised that mania may be the presenting syndrome of a seizure disorder that is secondary to an organic lesion.
继发性躁狂可能由代谢紊乱、中毒和/或结构性病变以及癫痫引起。作者描述了一名16岁女孩患有的类躁狂疾病，在该女孩中发现了右额叶动静脉畸形。最有效的药物治疗是锂盐和卡马西平联合使用。最终，该畸形被切除，从那以后患者未用药情况良好。由此提出一种可能性，即躁狂可能是继发于器质性病变的癫痫发作障碍的首发综合征。
