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腰椎骨平面化的罕见青少年骨化性纤维瘤病例。

Rare case of juvenile ossifying fibroma of the lumbar spine causing vertebra plana.

机构信息

Orthopaedics, All India Institute of Medical Sciences, New Delhi, Delhi, India.

Orthopaedics, All India Institute of Medical Sciences, New Delhi, Delhi, India

出版信息

BMJ Case Rep. 2021 Jan 18;14(1):e239097. doi: 10.1136/bcr-2020-239097.

Abstract

Juvenile ossifying fibroma (JOF) is a rare benign fibro-osseous tumour occurring in craniofacial bones of children and young adults. An 8-year-old girl presented with low back pain since 10 months. Plain radiographs revealed a vertebra plana-like lesion of L3 vertebra. CT scan showed an osteolytic lesion with areas of ground-glass appearance interspersed with bone flecks involving the entire body, pedicles and laminae of L3 with well-circumscribed cortical margins. Biopsy was done-histopathological findings showed cellular fibrous stroma with bony trabeculae-which, on corroboration with clinical and radiological findings noted previously, confirmed the diagnosis of JOF. The patient underwent preoperative angioembolisation, curettage and posterior stabilisation. At follow-up of 15 months, the patient was asymptomatic-imaging revealed residual tumour in pedicles-which however did not progress radiologically. The case raises the importance of including this rare condition as a differential diagnosis in children and reports successful outcome with subtotal resection.

摘要

骨化性纤维瘤(JOF)是一种罕见的良性纤维骨性肿瘤,发生在儿童和年轻成人的颅面骨中。一位 8 岁女孩因背痛 10 个月就诊。X 线平片显示 L3 椎体类椎体平板样病变。CT 扫描显示溶骨性病变,伴有磨玻璃样区域,其间散布着骨斑,累及 L3 的整个体部、椎弓根和椎板,边界清楚。进行了活检-组织病理学检查显示细胞纤维基质伴骨小梁-结合之前提到的临床和影像学发现,证实了 JOF 的诊断。患者接受了术前血管栓塞、刮除和后路稳定。15 个月随访时,患者无症状-影像学显示椎弓根残留肿瘤-但无进展。该病例强调了将这种罕见疾病作为儿童的鉴别诊断的重要性,并报告了次全切除的成功结果。

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