Orthopaedics, All India Institute of Medical Sciences, New Delhi, Delhi, India.
Orthopaedics, All India Institute of Medical Sciences, New Delhi, Delhi, India
BMJ Case Rep. 2021 Jan 18;14(1):e239097. doi: 10.1136/bcr-2020-239097.
Juvenile ossifying fibroma (JOF) is a rare benign fibro-osseous tumour occurring in craniofacial bones of children and young adults. An 8-year-old girl presented with low back pain since 10 months. Plain radiographs revealed a vertebra plana-like lesion of L3 vertebra. CT scan showed an osteolytic lesion with areas of ground-glass appearance interspersed with bone flecks involving the entire body, pedicles and laminae of L3 with well-circumscribed cortical margins. Biopsy was done-histopathological findings showed cellular fibrous stroma with bony trabeculae-which, on corroboration with clinical and radiological findings noted previously, confirmed the diagnosis of JOF. The patient underwent preoperative angioembolisation, curettage and posterior stabilisation. At follow-up of 15 months, the patient was asymptomatic-imaging revealed residual tumour in pedicles-which however did not progress radiologically. The case raises the importance of including this rare condition as a differential diagnosis in children and reports successful outcome with subtotal resection.
骨化性纤维瘤(JOF)是一种罕见的良性纤维骨性肿瘤,发生在儿童和年轻成人的颅面骨中。一位 8 岁女孩因背痛 10 个月就诊。X 线平片显示 L3 椎体类椎体平板样病变。CT 扫描显示溶骨性病变,伴有磨玻璃样区域,其间散布着骨斑,累及 L3 的整个体部、椎弓根和椎板,边界清楚。进行了活检-组织病理学检查显示细胞纤维基质伴骨小梁-结合之前提到的临床和影像学发现,证实了 JOF 的诊断。患者接受了术前血管栓塞、刮除和后路稳定。15 个月随访时,患者无症状-影像学显示椎弓根残留肿瘤-但无进展。该病例强调了将这种罕见疾病作为儿童的鉴别诊断的重要性,并报告了次全切除的成功结果。