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膝下病变严重肢体缺血的开放式和杂交治疗的结果。

Outcomes of open and hybrid treatments in below the knee pathology for critical limb threatening ischemia.

机构信息

Department of Vascular Surgery, Guy's and St Thomas' NHS Foundation Trust, St Thomas' Hospital, London, UK -

Department of Vascular Surgery, Guy's and St Thomas' NHS Foundation Trust, St Thomas' Hospital, London, UK.

出版信息

J Cardiovasc Surg (Torino). 2021 Apr;62(2):111-117. doi: 10.23736/S0021-9509.21.11654-4. Epub 2021 Jan 19.

Abstract

INTRODUCTION

The optimal management of below the knee pathology remains one of the most challenging areas for revascularization in patients presenting with critical limb threatening ischemia. Patients commonly have multilevel lesions and have a high amputation rate and associated mortality. This review aimed to assess the outcomes of below the knee revascularization strategies.

EVIDENCE ACQUISITION

An online literature search of medical databases for original articles or review articles was conducted using mesh terms.

EVIDENCE SYNTHESIS

Bypass surgery remains the gold standard for revascularization with good long-term outcomes with regards to patency, limb salvage, and quality of life but is associated with a higher morbidity than the endovascular approach. Given the increasing frailty of our patients, endovascular treatments have become the preferred strategy with results that are now equal to bypass. Hybrid surgery is an increasingly popular option as it combines the benefits of both endovascular and open surgery and although the evidence base is small the outcomes are encouraging.

CONCLUSIONS

Hybrid surgery offers promising results and could be considered in the treatment of multi-level lower limb arterial disease especially in high-risk patients or those who are not suitable for either open or endovascular techniques as a sole treatment modality.

摘要

引言

对于患有严重肢体缺血的患者,下肢病理的最佳治疗方法仍然是血管重建中最具挑战性的领域之一。患者通常存在多水平病变,并且截肢率和相关死亡率较高。本综述旨在评估膝下血管重建策略的结果。

证据获取

使用网状术语对医学数据库中的原始文章或综述文章进行了在线文献检索。

证据综合

旁路手术仍然是血管重建的金标准,在通畅性、肢体挽救和生活质量方面具有良好的长期效果,但与血管内治疗方法相比,发病率更高。鉴于我们的患者日益脆弱,血管内治疗已成为首选策略,其结果现在与旁路手术相当。杂交手术是一种越来越受欢迎的选择,因为它结合了血管内和开放手术的优点,尽管证据基础较小,但结果令人鼓舞。

结论

杂交手术提供了有希望的结果,特别是对于多水平下肢动脉疾病的治疗,可以考虑将其作为一种治疗方法,尤其是对于高危患者或不适合单独采用开放或血管内技术的患者。

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