Department of Paediatrics, Federal Medical Center, PMB 102004, Makurdi, Benue State,Nigeria.
Department of Paediatrics, University of Abuja Teaching Hospital, Gwagwalada,FCT,Abuja,Nigeria.
West Afr J Med. 2021 Jan;38(1):8-14.
Urinary abnormalities detected on routine urinalysis in asymptomatic children may be indicators of underlying kidney diseases.
This study was conducted to determine the prevalence and risk factors for asymptomatic proteinuria and haematuria in healthy primary school children in Abuja.
Using multi-staged sampling method, early morning mid-stream urine was collected from healthy school children from urban and rural primary schools in Gwagwalada Area Council of Abuja, Nigeria for the presence of proteinuria and haematuria using urinalysis strips. Those positive for proteinuria and haematuria were retested after two weeks for persistence abnormalities. Urine microscopy was also done for the persistent haematuria subjects, and biodata collected.
Of 861 urine samples analysed, 215 (25%) were from urban schools, and 646 (75%) from rural schools. There were 397 (46.1%) males. Their mean age was 9.5±2.1 years (range 6-12 years), with 9-10 years accounting for 36.4% of the study population. Proteinuria, haematuria, proteinuria+haematuria, persistent proteinuria, and persistent haematuria were seen in 7.0%, 10.6%, 3.6%, 4.2% and 5.5% of the subjects respectively. Microscopic haematuria was also documented in 5.2% subjects with persistent haematuria. Statistical significant association was seen between proteinuria with location of school (c2=9.529, p=0.002), and social class (c2=7.596, p=0.022). Significant association was also seen between haematuria and location of school (c2=14.218, p=0.001), social class (c2=11.290, p = 0.004).
There was high prevalence of asymptomatic proteinuria and haematuria among healthy primary school children from the study area. This underscores the importance of routine urinary screening program in primary schools for early identification of affected children for intervention.
在无症状儿童的常规尿检中发现的尿液异常可能是潜在肾脏疾病的指标。
本研究旨在确定阿布贾健康小学生无症状蛋白尿和血尿的患病率和危险因素。
使用多阶段抽样方法,从尼日利亚阿布贾 Gwagwalada 地区委员会的城市和农村小学采集健康学龄儿童的晨尿中段尿液,使用尿分析条检测蛋白尿和血尿。对蛋白尿和血尿阳性者进行两周后复查以确定异常是否持续存在。对持续血尿的受试者进行尿液显微镜检查,并收集生物数据。
在分析的 861 个尿液样本中,215 个(25%)来自城市学校,646 个(75%)来自农村学校。其中有 397 名(46.1%)男性。他们的平均年龄为 9.5±2.1 岁(范围为 6-12 岁),其中 36.4%的研究人群年龄为 9-10 岁。蛋白尿、血尿、蛋白尿+血尿、持续性蛋白尿和持续性血尿分别见于 7.0%、10.6%、3.6%、4.2%和 5.5%的受试者。在持续血尿的受试者中还记录到镜下血尿 5.2%。蛋白尿与学校位置(c2=9.529,p=0.002)和社会阶层(c2=7.596,p=0.022)之间存在统计学显著关联。血尿与学校位置(c2=14.218,p=0.001)和社会阶层(c2=11.290,p=0.004)之间也存在显著关联。
在所研究地区的健康小学生中,无症状蛋白尿和血尿的患病率很高。这突显了在小学开展常规尿液筛查计划的重要性,以便及早发现受影响的儿童并进行干预。