由复方利尿剂氢氯噻嗪和氨苯蝶啶引起的亚急性皮肤型红斑狼疮样药物疹。

Subacute cutaneous lupus erythematosus-like drug eruption due to combination diuretic hydrochlorothiazide and triamterene.

作者信息

Darken M, McBurney E I

机构信息

Department of Dermatology, Louisiana State University School of Medicine, Slidell.

出版信息

J Am Acad Dermatol. 1988 Jan;18(1 Pt 1):38-42. doi: 10.1016/s0190-9622(88)70005-5.

DOI:10.1016/s0190-9622(88)70005-5

PMID:3346407

Abstract

Three patients taking a frequently prescribed diuretic combination of hydrochlorothiazide and triamterene developed eruptions resembling subacute cutaneous lupus erythematosus. Histopathology of the skin biopsies of all three patients was consistent with subacute cutaneous lupus erythematosus. On discontinuation of the diuretic drug, the cutaneous eruptions cleared.

摘要

三名服用常用利尿剂组合氢氯噻嗪和氨苯蝶啶的患者出现了类似亚急性皮肤型红斑狼疮的皮疹。所有三名患者的皮肤活检组织病理学与亚急性皮肤型红斑狼疮一致。停用利尿药后，皮肤皮疹消退。