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儿童和青年期饮食与成年发病多发性硬化症的探索性研究。

An exploratory study of diet in childhood and young adulthood and adult-onset multiple sclerosis.

机构信息

School of Public Health, Curtin University, Bentley, WA, Australia.

Department of Natural Sciences, Galway Mayo Institute of Technology, Galway, Ireland.

出版信息

Mult Scler. 2021 Sep;27(10):1611-1614. doi: 10.1177/1352458520986964. Epub 2021 Jan 19.

Abstract

There is little evidence on the role of diet in childhood/adolescence and multiple sclerosis (MS) in adulthood. The MS Sunshine Study recruited adults with recent-onset MS ( = 602) and matched controls ( = 653). Of these, 84% provided dietary recall for specific ages between childhood and young adulthood (6-10, 11-15 and 16-20 years). We used logistic regression to test associations between age-specific diet and case-control status. Consumption of fruit (all ages), yoghurt (all ages) and legumes (11-15 years) was associated with lower probability of adult-onset MS (all  < 0.05). These results suggest that healthy dietary habits between childhood and young adulthood may reduce MS risk.

摘要

关于饮食在儿童/青少年时期和成年后患多发性硬化症(MS)中的作用,目前几乎没有证据。MS 阳光研究招募了近期发病的成年 MS 患者(n=602)和匹配对照者(n=653)。其中,84%的人提供了特定年龄段(6-10 岁、11-15 岁和 16-20 岁)的饮食回忆。我们使用逻辑回归检验了特定年龄段饮食与病例对照状态之间的关联。水果(所有年龄段)、酸奶(所有年龄段)和豆类(11-15 岁)的消费与成年后 MS 的发病概率较低相关(均 < 0.05)。这些结果表明,儿童和青年时期的健康饮食习惯可能会降低 MS 的发病风险。

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本文引用的文献

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The role of diet in multiple sclerosis: A review.饮食在多发性硬化中的作用:综述。
Nutr Neurosci. 2018 Jul;21(6):377-390. doi: 10.1080/1028415X.2017.1303016. Epub 2017 Mar 24.

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