Kint A, Baran R
Clinic of Dermatology, Akademisch Ziekenhuis, University of Ghent, Belgium.
J Am Acad Dermatol. 1988 Feb;18(2 Pt 1):369-72. doi: 10.1016/s0190-9622(88)70054-7.
Fifteen periungual fibromas from nine patients were studied histologically. The lesions were elongated. Capillaries were found in the distal part surrounded by thin collagen bundles whereas the proximal part was made up of dense, closely packed fibers. The epidermis covering the tumor appeared to be connected with the nail fold. The dense collagen of the lesion faded into the normal structure of the cutis of the proximal nail fold. Periungual fibromas can be subdivided into (1) fibrokeratomas originating from the dermal connective tissue and (2) fibrokeratomas originating from the proximal nail fold.
对9例患者的15个甲周纤维瘤进行了组织学研究。病变呈细长形。在远端部分发现有毛细血管，周围有薄的胶原束，而近端部分由密集、紧密排列的纤维组成。覆盖肿瘤的表皮似乎与甲襞相连。病变的致密胶原逐渐融入近端甲襞皮肤的正常结构。甲周纤维瘤可分为(1)起源于真皮结缔组织的纤维角化瘤和(2)起源于近端甲襞的纤维角化瘤。
