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Impact of prothrombin complex concentrate and fresh frozen plasma on correction of haemostatic abnormalities in bleeding patients undergoing cardiac surgery (PROPHESY trial results).

作者信息

Green L, Roberts N, Platton S, O'Brien B, Agarwal S, Gill R, Klein A A, Stanworth S, Cooper J

机构信息

William Harvey Research Institute, Queen Mary University of London, UK.

Barts Health NHS Trust, London, UK.

出版信息

Anaesthesia. 2021 Jul;76(7):997-1000. doi: 10.1111/anae.15395. Epub 2021 Jan 19.

DOI:10.1111/anae.15395
PMID:33464560
Abstract
摘要

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1
Impact of prothrombin complex concentrate and fresh frozen plasma on correction of haemostatic abnormalities in bleeding patients undergoing cardiac surgery (PROPHESY trial results).凝血酶原复合物浓缩剂和新鲜冰冻血浆对心脏手术出血患者止血异常纠正的影响(PROPHESY试验结果)
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BMJ Open. 2024 Aug 21;14(8):e091381. doi: 10.1136/bmjopen-2024-091381.
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A pragmatic pilot phase II randomised controlled trial of prothrombin complex concentrates (PCC) versus fresh frozen plasma (FFP) in adult patients who are undergoing heart surgery (PROPHESY).一项关于在接受心脏手术的成年患者中使用凝血酶原复合物浓缩物(PCC)与新鲜冷冻血浆(FFP)的实用二期随机对照试验(PROPHESY)。
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引用本文的文献

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Prothrombin complex concentrate in cardiac surgery for the treatment of coagulopathic bleeding.心脏手术中使用凝血酶原复合物浓缩物治疗凝血功能障碍性出血。
Cochrane Database Syst Rev. 2022 Nov 21;11(11):CD013551. doi: 10.1002/14651858.CD013551.pub2.
2
Effect on haemostasis of different replacement fluids during therapeutic plasma exchange-A comparative multicentre observational study.不同置换液在治疗性血浆置换中对止血功能的影响:一项比较多中心观察性研究。
J Clin Apher. 2022 Dec;37(6):534-543. doi: 10.1002/jca.22008. Epub 2022 Aug 24.
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Coagulation and Transfusion Updates From 2021.
2021 年凝血和输血更新
J Cardiothorac Vasc Anesth. 2022 Sep;36(9):3447-3458. doi: 10.1053/j.jvca.2022.03.042. Epub 2022 Apr 6.