Department of Psychology, Louisiana State University, Baton Rouge, Louisiana, United States of America.
Pennington Biomedical Research Center, Baton Rouge, Louisiana, United States of America.
PLoS One. 2021 Jan 19;16(1):e0244962. doi: 10.1371/journal.pone.0244962. eCollection 2021.
The coronavirus disease pandemic has brought a new urgency for the development and deployment of web-based applications which complement, and offer alternatives to, traditional one-on-one consultations and pencil-and-paper (PaP) based assessments that currently dominate clinical research. We have recently developed a web-based application that can be used for the self-administered collection of patient demographics, self-rated health, depression and anxiety, and cognition as part of a single platform. In this study we report the findings from a study with 155 cognitively healthy older adults who received established PaP versions, as well as our novel computerized measures of self-rated health, depression and anxiety, and cognition. Moderate to high correlations were observed between PaP and web- based measures of self-rated health (r = 0.77), depression and anxiety (r = 0.72), and preclinical Alzheimer's disease cognitive composite (PACC) (r = .61). Test-retest correlations were variable with high correlations for a measure of processing speed and a measure of delayed episodic memory. Taken together, these data support the feasibility and validity of utilization of this novel web-based platform as a new alternative for collecting patient demographics and the assessment of self-rated health, depression and anxiety, and cognition in the elderly.
冠状病毒病大流行使得开发和部署基于网络的应用程序变得更加紧迫，这些应用程序可以补充传统的一对一咨询和基于纸笔（PaP）的评估方法，而这些方法目前在临床研究中占主导地位。我们最近开发了一种基于网络的应用程序，可用于自我管理患者人口统计学、自我评估健康、抑郁和焦虑以及认知等信息的收集，作为单一平台的一部分。在这项研究中，我们报告了一项针对 155 名认知健康的老年人的研究结果，这些老年人接受了传统的 PaP 版本，以及我们新的计算机化的自我评估健康、抑郁和焦虑以及认知的测量。PaP 和基于网络的自我评估健康（r = 0.77）、抑郁和焦虑（r = 0.72）以及临床前阿尔茨海默病认知综合指标（PACC）（r =.61）的测量之间存在中度到高度相关性。测试-重测相关性各不相同，对于处理速度的测量和延迟情节记忆的测量具有高度相关性。这些数据表明，这种新的基于网络的平台可用于收集患者人口统计学信息以及评估老年人的自我评估健康、抑郁和焦虑以及认知，其可行性和有效性得到了支持。
