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SARS-CoV-2 胎盘炎：母体 COVID-19 的一种不常见并发症。

SARS-CoV-2 placentitis: An uncommon complication of maternal COVID-19.

机构信息

INFANT Centre, 5th Floor, Cork University Maternity Hospital, Wilton, Cork, Ireland.

INFANT Centre, 5th Floor, Cork University Maternity Hospital, Wilton, Cork, Ireland.

出版信息

Placenta. 2021 Jan 15;104:261-266. doi: 10.1016/j.placenta.2021.01.012. Epub 2021 Jan 11.

DOI:10.1016/j.placenta.2021.01.012
PMID:33465727
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7832228/
Abstract

We present a case of third trimester pregnancy complicated by SARS-CoV-2 infection and subsequent reduced fetal movements, resulting in emergency Caesarean delivery with demonstrable placental SARS-CoV-2 placentitis. We show through illustration of this case and literature review that SARS-Co-V-2 placentitis is an uncommon but readily recognisable complication of maternal SARS-CoV-2 infection that may be a marker of potential vertical transmission and that may have the capacity to cause fetal compromise through a direct injurious effect on the placenta.

摘要

我们报告了一例妊娠晚期合并 SARS-CoV-2 感染及随后胎动减少的病例，导致紧急剖宫产，胎盘组织中检测到 SARS-CoV-2 感染。通过本病例的阐述和文献复习，我们发现 SARS-CoV-2 胎盘炎是一种罕见但容易识别的母胎 SARS-CoV-2 感染并发症，可能是垂直传播的潜在标志物，并可能通过直接损伤胎盘对胎儿造成损害。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e84/7832228/d5406cd57182/gr3_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e84/7832228/7b6fad4db06b/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e84/7832228/bb43cbc096ae/gr2_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e84/7832228/d5406cd57182/gr3_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e84/7832228/7b6fad4db06b/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e84/7832228/bb43cbc096ae/gr2_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e84/7832228/d5406cd57182/gr3_lrg.jpg

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J Pediatric Infect Dis Soc. 2021 May 28;10(5):556-561. doi: 10.1093/jpids/piaa153.
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A structured review of placental morphology and histopathological lesions associated with SARS-CoV-2 infection.与 SARS-CoV-2 感染相关的胎盘形态和组织病理学病变的系统评价。
Placenta. 2020 Nov;101:13-29. doi: 10.1016/j.placenta.2020.08.018. Epub 2020 Aug 23.
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Clinical manifestations, risk factors, and maternal and perinatal outcomes of coronavirus disease 2019 in pregnancy: living systematic review and meta-analysis.
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Public Health Nurs. 2025 May-Jun;42(3):1272-1287. doi: 10.1111/phn.13542. Epub 2025 Mar 13.
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Similar Spatial Expression of Immune-Related Proteins in SARS-CoV-2 Placentitis and Chronic Histiocytic Intervillositis.SARS-CoV-2 胎盘炎和慢性组织细胞绒毛间炎中免疫相关蛋白的相似空间表达
Eur J Immunol. 2025 Jan;55(1):e202451386. doi: 10.1002/eji.202451386.
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