Division of Cardiology, Department of Internal Medicine.
Department of Radiology.
Medicine (Baltimore). 2021 Jan 15;100(2):e24044. doi: 10.1097/MD.0000000000024044.
Cardiac primary spindle cell sarcoma is 1 of the rarest cardiac malignancies, with only a few cases reported so far. Herein, we reported a case of left atrial spindle cell sarcoma diagnosed and treated by a multidisciplinary approach, and retrospectively reviewed other reported cases.
A 49-year-old woman presented to our hospital with 2 weeks of gradual onset of dyspnea on exertion, dry cough and subacute fever.
The patient was initially revealed a left atrium mass by 2-dimensional transthoracic echocardiography. Based on the contrast-enhanced echocardiography and cardiac magnetic resonance imaging, she was subsequently suggested to have a cardiac malignant tumor. And the post-operative histopathology confirmed the tumor to be a cardiac primary spindle cell sarcoma.
The tumor was completely resected using autotransplantation. The patient was referred for polychemotherapy afterwards.
Our patient underwent the tumor resection, with subsequent adjuvant polychemotherapy, and the tumor has not recurred during 12 months of follow-up.
Due to the rarity of these tumors and nonspecific symptoms, they are often difficult to diagnose preoperatively and missed occasionally. Thus, improving our understanding of the disease and facilitating its early diagnosis are essential.
心脏原发性梭形细胞肉瘤是最罕见的心脏恶性肿瘤之一，迄今为止仅报道了少数几例。在此，我们通过多学科方法报告了一例左心房梭形细胞肉瘤的诊断和治疗，并回顾性分析了其他已报道的病例。
一名 49 岁女性因逐渐出现劳力性呼吸困难、干咳和亚急性发热 2 周而就诊于我院。
二维经胸超声心动图最初显示左心房肿块。根据对比增强超声心动图和心脏磁共振成像，随后提示该患者患有心脏恶性肿瘤。术后组织病理学证实为心脏原发性梭形细胞肉瘤。
使用自体移植完全切除肿瘤。随后患者被转介进行多化疗。
我们的患者接受了肿瘤切除术，随后进行了辅助多化疗，在 12 个月的随访期间，肿瘤未复发。
由于这些肿瘤罕见且症状无特异性，术前通常难以诊断，偶尔会被漏诊。因此，提高对该病的认识并促进早期诊断至关重要。
