Human Nutrition Research Unit, Department of Agricultural, Food & Nutritional Science, University of Alberta, Edmonton, AB T6G 2E1, Canada.
Alberta Diabetes Institute, University of Alberta, Edmonton, AB T6G 2E1, Canada.
Nutrients. 2021 Jan 5;13(1):155. doi: 10.3390/nu13010155.
The aim of this study was to compare the impact of a high-protein meal replacement (HP-MR) versus a control (CON) breakfast on exercise metabolism. In this acute, randomized controlled, cross-over study, participants were allocated into two isocaloric arms: (a) HP-MR: 30% carbohydrate, 43% protein, and 27% fat; (b) CON: 55% carbohydrate, 15% protein, and 30% fat. Following breakfast, participants performed a moderate-intensity aerobic exercise while inside a whole-body calorimetry unit. Energy expenditure, macronutrient oxidation, appetite sensations, and metabolic blood markers were assessed. Forty-three healthy, normal-weight adults (24 males) participated. Compared to the CON breakfast, the HP-MR produced higher fat oxidation (1.07 ± 0.33 g/session; = 0.003) and lower carbohydrate oxidation (-2.32 ± 0.98 g/session; = 0.023) and respiratory exchange ratio (-0.01 ± 0.00; = 0.003) during exercise. After exercise, increases in hunger were lower during the HP-MR condition. Changes in blood markers from the fasting state to post-exercise during the HP-MR condition were greater for insulin, peptide tyrosine-tyrosine, and glucagon-like peptide 1, and lower for low-density lipoprotein cholesterol, triglyceride, and glycerol. Our primary findings were that an HP-MR produced higher fat oxidation during the exercise session, suppression of hunger, and improved metabolic profile after it.
本研究旨在比较高蛋白膳食替代(HP-MR)与对照(CON)早餐对运动代谢的影响。在这项急性、随机对照、交叉研究中,参与者被分配到两个等热量组:(a)HP-MR:30%碳水化合物、43%蛋白质和 27%脂肪;(b)CON:55%碳水化合物、15%蛋白质和 30%脂肪。早餐后,参与者在全身热量计室内进行中等强度的有氧运动。评估能量消耗、宏量营养素氧化、食欲感觉和代谢血液标志物。43 名健康、正常体重的成年人(24 名男性)参与了研究。与 CON 早餐相比,HP-MR 在运动期间产生更高的脂肪氧化(1.07±0.33g/session;=0.003)和更低的碳水化合物氧化(-2.32±0.98g/session;=0.023)和呼吸交换率(-0.01±0.00;=0.003)。运动后,HP-MR 条件下饥饿感增加较低。HP-MR 条件下,从空腹状态到运动后,胰岛素、肽酪氨酸-酪氨酸和胰高血糖素样肽 1 的血液标志物变化更大,而低密度脂蛋白胆固醇、甘油三酯和甘油的变化更小。我们的主要发现是,HP-MR 在运动期间产生更高的脂肪氧化,抑制饥饿感,并改善运动后的代谢谱。