Chapelle P A, Roby-Brami A, Yakovleff A, Bussel B
Service de Rééducation Neurologique, Hôpital Raymond Poincaré, Garches, France.
J Neurol Neurosurg Psychiatry. 1988 Feb;51(2):197-202. doi: 10.1136/jnnp.51.2.197.
This study was of 135 patients with a complete spinal cord section suffered from loss of ejaculation. The spinal cord injuries were classified following the upper and the lower limits of the lesion. The volume of the testes of the patients and of 13 normal control subjects were measured. Physostigmine allowed 75 patients to ejaculate and 15 of them procreated. The possibility of ejaculation after physostigmine mainly depended on the integrity of the T12-L2 metamers. The testicular volume was significantly smaller in patients with a lesion including the T12 metamer than in patients with a lesion sparing the T12 metamer. Six patients with a lesion including the T12 metamer had testicular atrophy. This suggests that T12 segment plays a role in testicular function in paraplegic patients.
本研究针对135例因脊髓完全横断而出现射精功能丧失的患者展开。根据损伤的上下限对脊髓损伤进行分类。测量了这些患者以及13名正常对照者的睾丸体积。毒扁豆碱使75例患者能够射精，其中15例患者生育。毒扁豆碱治疗后射精的可能性主要取决于胸12 -腰2节段的完整性。与未累及胸12节段的损伤患者相比，累及胸12节段的损伤患者的睾丸体积明显较小。6例累及胸12节段的损伤患者出现睾丸萎缩。这表明胸12节段在截瘫患者的睾丸功能中发挥作用。
