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膝关节伸展力量测量显示可能存在的肌肉减少症与健康相关结局相关,并且是髋部骨折手术后患者1年死亡率的有力预测指标。

Knee Extension Strength Measures Indicating Probable Sarcopenia Is Associated with Health-Related Outcomes and a Strong Predictor of 1-Year Mortality in Patients Following Hip Fracture Surgery.

作者信息

Kristensen Morten Tange, Hulsbæk Signe, Faber Louise Lohmann, Kronborg Lise

机构信息

Physical Medicine and Rehabilitation Research-Copenhagen (PMR-C), Departments of Physical Therapy and Orthopedic Surgery, Amager-Hvidovre Hospital, University of Copenhagen, 2650 Hvidovre, Denmark.

Institute of Clinical Medicine, University of Copenhagen, Nørrebro, 2200 Copenhagen, Denmark.

出版信息

Geriatrics (Basel). 2021 Jan 15;6(1):8. doi: 10.3390/geriatrics6010008.

Abstract

To examine if knee-extension strength (KES) measures indicating probable sarcopenia are associated with health-related outcomes and if KES and hand grip strength (HGS) measures are associated with 1-year mortality after hip fracture. Two groups of older patients with hip fracture had either HGS ( = 32) or KES ( = 150) assessed during their acute hospital stay. Cut-points for HGS (<27 kg for men and <16 kg for women), and cut-points for maximal isometric KES (non-fractured limb), being the lowest sex-specific quintile (<23.64 kg for men and <15.24 kg for women), were used to examine association with health-related outcomes and 1-year mortality. Overall, 1-year mortality was 12.6% in the two strength groups, of which 47% (HGS) and 46% (KES) respectively, were classified as probable sarcopenia. Probable sarcopenia patients (KES) had lower prefracture function, performed poorly in mobility measures and expressed a greater concern of falling compared to their stronger counterparts. Hazard ratio for 1-year mortality was 2.7 (95%CI = 0.49-14.7, = 0.3) for HGS and 9.8 (95%CI = 2.2-43.0, = 0.002) for KES for probable sarcopenia patients compared to those not. Sex-specific KES measures indicating sarcopenia is associated with health-related outcomes and a strong predictor of 1-year mortality after hip fracture.

摘要

为了研究表明可能存在肌肉减少症的膝关节伸展力量(KES)测量指标是否与健康相关结局相关,以及KES和握力(HGS)测量指标是否与髋部骨折后的1年死亡率相关。两组老年髋部骨折患者在急性住院期间接受了HGS(n = 32)或KES(n = 150)评估。使用HGS的切点(男性<27 kg,女性<16 kg)以及最大等长KES(非骨折肢体)的切点,即性别特异性最低五分位数(男性<23.64 kg,女性<15.24 kg),来检验与健康相关结局和1年死亡率的关联。总体而言,两个力量组的1年死亡率为12.6%,其中分别有47%(HGS)和46%(KES)被归类为可能存在肌肉减少症。与较强的同龄人相比,可能存在肌肉减少症的患者(KES)骨折前功能较低,在 mobility 测量中表现较差,并且对跌倒的担忧更大。与未患可能存在肌肉减少症的患者相比,可能存在肌肉减少症的患者中,HGS的1年死亡率风险比为2.7(95%CI = 0.49 - 14.7,P = 0.3),KES为9.8(95%CI = 2.2 - 43.0,P = 0.002)。表明存在肌肉减少症的性别特异性KES测量指标与健康相关结局相关,并且是髋部骨折后1年死亡率的有力预测指标。 (注:原文中“mobility measures”未明确中文释义,保留英文)

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/584c/7839049/2ed82c23afc5/geriatrics-06-00008-g001.jpg

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本文引用的文献

1
Longitudinal changes in physical activity levels and fear of falling after hip fracture.
Physiother Res Int. 2021 Jan;26(1):e1884. doi: 10.1002/pri.1884. Epub 2020 Nov 12.
2
Lower Limb Strength Profile in Elderly with Different Pathologies: Comparisons with Healthy Subjects.
Geriatrics (Basel). 2020 Oct 22;5(4):83. doi: 10.3390/geriatrics5040083.
3
Early mobilisation reduces the risk of in-hospital mortality following hip fracture.
Eur Geriatr Med. 2020 Aug;11(4):527-533. doi: 10.1007/s41999-020-00317-y. Epub 2020 Apr 9.
4
The high prevalence of sarcopenia and its associated outcomes following hip surgery in Taiwanese geriatric patients with a hip fracture.
J Formos Med Assoc. 2020 Dec;119(12):1807-1816. doi: 10.1016/j.jfma.2020.02.004. Epub 2020 Feb 25.
5
Exercise for preventing falls in older people living in the community: an abridged Cochrane systematic review.
Br J Sports Med. 2020 Aug;54(15):885-891. doi: 10.1136/bjsports-2019-101512. Epub 2019 Dec 2.
10
Sarcopenia: new definitions, same limitations.
Age Ageing. 2019 Sep 1;48(5):613-614. doi: 10.1093/ageing/afz087.

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