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英国妇科癌症学会/英国妇科病理学会共识:英国卵巢癌 1/2 变体种系和肿瘤检测。

British Gynaecological Cancer Society/British Association of Gynaecological Pathology consensus for germline and tumor testing for 1/2 variants in ovarian cancer in the United Kingdom.

机构信息

Gynaecological Oncology, Pan-Birmingham Gynaecological Cancer Centre, Birmingham, UK

Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UK.

出版信息

Int J Gynecol Cancer. 2021 Feb;31(2):272-278. doi: 10.1136/ijgc-2020-002112. Epub 2021 Jan 19.

Abstract

The British Gynecological Cancer Society and the British Association of Gynecological Pathologists established a multidisciplinary consensus group comprising experts in surgical gynecological oncology, medical oncology, genetics, and laboratory science, and clinical nurse specialists to identify the optimal pathways to germline and tumor testing in patients with ovarian cancer in routine clinical practice. In particular, the group explored models of consent, quality standards identified at pathology laboratories, and experience and data from pioneering cancer centers. The group liaised with representatives from ovarian cancer charities to also identify patient perspectives that would be important to implementation. Recommendations from these consensus group deliberations are presented in this manuscript.

摘要

英国妇科癌症学会和英国妇科病理学家协会成立了一个多学科共识小组,成员包括妇科肿瘤学、肿瘤内科、遗传学和实验室科学方面的专家,以及临床护士专家,以确定在常规临床实践中对卵巢癌患者进行种系和肿瘤检测的最佳途径。特别是,该小组探讨了同意模式、病理学实验室确定的质量标准,以及来自开创性癌症中心的经验和数据。该小组还与卵巢癌慈善机构的代表联系,以确定对实施具有重要意义的患者观点。这些共识小组审议的建议在本手稿中提出。

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