Kamada Yosuke, Ogino Shinpei, Koizumi Noriaki, Fujiki Hiroshi, Nakamura Kenji, Sakakura Chohei
Dept. of General Surgery, Akashi City Hospital.
Gan To Kagaku Ryoho. 2020 Dec;47(13):2427-2429.
A 63-year-old man underwent proximal gastrectomy for gastrointestinal stromal tumor(GIST)of the stomach 19 years ago. Local recurrence of GIST of the stomach occurred 13 years later, and the tumor was resected. Since then, he had adjuvant chemotherapy. Six years later, computed tomography revealed a soft-tissue shadow at the left lateral side of the stomach, and positron emission tomography also revealed fluorodeoxyglucose uptake at the same site. The recurrence of GIST was suspected, and therefore laparoscopic resection was performed. The operative time was 70 minutes. Blood loss was 10 g. Immunohistochemical examination showed positivity for c-kit and CD34, leading to a diagnosis of recurrence of GIST. The postoperative course was uneventful, and the patient was discharged on the fifth postoperative day. At present, the patient is alive without adjuvant chemotherapy 13 months since surgery. GIST may recur 10 years or more after surgery. Therefore, long-term surveillance seems to be mandatory.
一名63岁男性19年前因胃胃肠道间质瘤（GIST）接受了近端胃切除术。13年后胃GIST出现局部复发，肿瘤被切除。从那时起，他接受了辅助化疗。6年后，计算机断层扫描显示胃左侧有软组织阴影，正电子发射断层扫描也显示同一部位有氟脱氧葡萄糖摄取。怀疑GIST复发，因此进行了腹腔镜切除术。手术时间为70分钟。失血10克。免疫组织化学检查显示c-kit和CD34呈阳性，诊断为GIST复发。术后过程顺利，患者术后第5天出院。目前，患者术后13个月未接受辅助化疗，仍然存活。GIST术后可能10年或更长时间复发。因此，长期监测似乎是必要的。
