Li H F, Chan F H, Poon P W, Hwang J C, Chan W S
Department of Electrical Engineering, University of Hong Kong.
J Biomed Eng. 1988 Jan;10(1):14-24. doi: 10.1016/0141-5425(88)90022-2.
An evoked response may be assumed to consist of synchronous electrical activities of groups of neurons in response to a stimulus. Unfortunately, this response is usually weak and often masked by the background EEG activity generated spontaneously by the brain. In order to extract the embedded evoked response we have employed the theory of maximum length sequence, assuming only a temporal linearity of the system from which measurements are taken. The technique has been applied successfully with the aid of a microcomputer. The system also supports the same measurement by a conventional averaging technique. The results of the two are compared, indicating the advantages of the maximum length technique: improved signal-to-noise ratio, repeatability and speed.
诱发反应可被认为是一组神经元对刺激做出的同步电活动。不幸的是,这种反应通常很微弱,并且常常被大脑自发产生的背景脑电图活动所掩盖。为了提取嵌入的诱发反应,我们采用了最大长度序列理论,仅假设进行测量的系统具有时间线性。借助微型计算机,该技术已成功应用。该系统还支持通过传统的平均技术进行相同的测量。对两者的结果进行了比较,表明了最大长度技术的优势:提高了信噪比、可重复性和速度。