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脑卒中后早期抑郁的症状群:一项混合方法研究。

Symptom clusters of early-stage poststroke depression: A mixed-methods study.

作者信息

Chen Junya, Li Yun, Liu Jing, Zhang Yi, Zeng Yawei, Chen Mengjiao, Ding Weiwei, Lu Zhongqiu, Xu Hongbo, Li Jufang

机构信息

School of Nursing, Wenzhou Medical University, Wenzhou, China.

The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.

出版信息

Nurs Open. 2021 Sep;8(5):2488-2497. doi: 10.1002/nop2.772. Epub 2021 Jan 20.

DOI:10.1002/nop2.772
PMID:33471441
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8363377/
Abstract

AIM

To identify the symptom clusters of early-stage poststroke depression (PSD) and provide an in-depth understanding of the symptoms.

DESIGN

A mixed-methods study with a convenient sampling method was used.

METHODS

A cross-sectional questionnaire survey in 231 stroke patients and semi-structured interviews in 14 stroke patients were conducted in the neurological department of a comprehensive hospital in Southeast China. Data from the questionnaire survey were analysed through descriptive and exploratory factor analyses; data from the semi-structured interview were transcribed verbatim and analysed through inductive content analysis. This study adheres to the GRAMMS checklist.

RESULTS

Exploratory factor analysis revealed six symptom clusters of early-stage PSD that accounted for an ideal variance in PSD: nervous, wakefulness, emotional, dull, guilt and low mood. Further, inductive content analysis revealed five themes that were like the above symptom clusters, except for the dull symptom cluster.

摘要

目的

识别脑卒中后早期抑郁(PSD)的症状群,并深入了解这些症状。

设计

采用便利抽样法进行混合方法研究。

方法

在中国东南部一家综合医院的神经科,对231例脑卒中患者进行了横断面问卷调查,并对14例脑卒中患者进行了半结构式访谈。问卷调查数据通过描述性和探索性因素分析进行分析;半结构式访谈数据逐字转录,并通过归纳性内容分析进行分析。本研究遵循GRAMMS清单。

结果

探索性因素分析揭示了PSD早期的六个症状群,这些症状群在PSD中占理想的方差:紧张、觉醒、情绪、迟钝、内疚和情绪低落。此外,归纳性内容分析揭示了五个与上述症状群相似的主题,但迟钝症状群除外。

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本文引用的文献

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Properties of the Early Symptom Measurement of Post-Stroke Depression: Concurrent Criterion Validity and Cutoff Scores.脑卒中后抑郁早期症状测量的特性:同时效标效度和截断分数。
J Nurs Res. 2020 Aug;28(4):e107. doi: 10.1097/jnr.0000000000000380.
2
Relationship between pre-stroke physical activity and symptoms of post-stroke anxiety and depression: An observational study.卒中前体力活动与卒中后焦虑和抑郁症状的关系:一项观察性研究。
J Rehabil Med. 2019 Oct 29;51(10):755-760. doi: 10.2340/16501977-2610.
3
Symptoms of depression and cognitive impairment in young adults after stroke/transient ischemic attack.
青年脑卒中/短暂性脑缺血发作后抑郁和认知障碍的症状。
Psychiatry Res. 2019 Sep;279:361-363. doi: 10.1016/j.psychres.2019.06.022. Epub 2019 Jul 1.
4
Post stroke depression and risk of stroke recurrence and mortality: A systematic review and meta-analysis.卒中后抑郁与卒中复发和死亡风险:系统评价和荟萃分析。
Ageing Res Rev. 2019 Mar;50:102-109. doi: 10.1016/j.arr.2019.01.013. Epub 2019 Jan 31.
5
Does depression after stroke negatively influence physical disability? A systematic review and meta-analysis of longitudinal studies.中风后抑郁是否会对身体残疾产生负面影响?一项对纵向研究的系统评价和荟萃分析。
J Affect Disord. 2019 Mar 15;247:45-56. doi: 10.1016/j.jad.2018.12.082. Epub 2018 Dec 25.
6
Acute post stroke depression at a Primary Stroke Center in the Middle East.中东初级卒中中心的急性卒中后抑郁。
PLoS One. 2018 Dec 20;13(12):e0208708. doi: 10.1371/journal.pone.0208708. eCollection 2018.
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