Digestive Diseases Center, Showa University Koto Toyosu Hospital, Tokyo, Japan.
Department of Gastroenterology and Hepatology, Hospital Universitario Ramón y Cajal, Universidad de Alcalá, IRYCIS, Madrid, Spain.
Endoscopy. 2022 Feb;54(2):158-162. doi: 10.1055/a-1364-4160. Epub 2021 Mar 16.
This study aimed to assess the feasibility and efficacy of the novel loop 9 method of gastrointestinal (GI) defect closure. METHODS : 20 patients underwent a GI procedure that required defect closure. Loop 9 can be delivered through a single instrument channel (3.2 mm) and released at the defect site. After it has been anchored by two clips positioned on opposite sides of the defect edge, the loop 9 is tightened by pulling the end of the suture intraluminally using biopsy forceps. Additional clips are placed to achieve complete closure. The primary outcome was complete closure rate. The secondary outcomes were closure time, sustained closure rate, and adverse events. RESULTS : Complete closure was achieved in 100 % of cases. The mean size of the mucosal defects was 17.5 mm (range 10-55 mm). The median closure time was 14 minutes. The sustained closure rate was 90 %. No adverse events were noted. CONCLUSIONS : The loop 9 technique is feasible and effective in achieving complete and sustained closure of therapeutic endoscopy-related GI defects.
本研究旨在评估新型环 9 法胃肠（GI）缺损闭合的可行性和疗效。
20 例患者接受了需要缺损闭合的 GI 手术。环 9 可通过单个器械通道（3.2mm）输送，并在缺损部位释放。在通过定位在缺损边缘相对侧的两个夹将环 9 锚定之后，通过使用活检钳从管腔内拉动缝线的末端将环 9 收紧。放置附加夹以实现完全闭合。主要结局是完全闭合率。次要结局是闭合时间、持续闭合率和不良事件。
100%的病例实现了完全闭合。黏膜缺损的平均大小为 17.5mm（范围 10-55mm）。中位闭合时间为 14 分钟。持续闭合率为 90%。未观察到不良事件。
环 9 技术在实现治疗性内镜相关 GI 缺损的完全和持续闭合方面是可行且有效的。
