来自[具体来源未给出]的线粒体DNA基因组亚基（和）基因的ATP合酶序列分析。
Sequence analysis of the ATP synthase of subunits ( and ) genes of mitochondrial DNA genome from .
作者信息
Hu Yaodong, Pang Huizhong, Ling Shanshan, Wei Rongping, Zhu Yun, Zhang Hemin, Li Diyan, Li Desheng, Wang Chengdong
机构信息
Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, Sichuan Agricultural University, Chengdu, China.
China Conservation and Research Center for the Giant Panda, Wolong, China.
出版信息
Mitochondrial DNA B Resour. 2018 Oct 9;3(2):1092-1093. doi: 10.1080/23802359.2018.1424574.
To explore the effects of the mutations of and genes on energy metabolism and genetic structure, we sequenced the and genes of . Our results showed that is a conserved gene and gene is positively selected during the evolution of the giant panda population with a low genetic diversity. Population expansion was observed in the giant panda group. The T179C mutation on Haplotype7 made the production of a potential phosphorylation site. This non-synonymous mutation may occur at the post-translational modification site that have a potential effect on the function of ATP synthase, related to the maintenance of body temperature of pandas at low metabolic rates.
为了探究 基因和 基因的突变对能量代谢和遗传结构的影响，我们对 的 和 基因进行了测序。我们的结果表明， 是一个保守基因， 基因在大熊猫种群进化过程中受到正选择，且遗传多样性较低。在大熊猫群体中观察到了种群扩张。单倍型7上的T179C突变产生了一个潜在的磷酸化位点。这种非同义突变可能发生在翻译后修饰位点，对ATP合酶的功能有潜在影响，而ATP合酶与大熊猫在低代谢率下维持体温有关。
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