Zinc treatment of outpatient COVID-19: A retrospective review of 28 consecutive patients.
作者信息
Finzi Eric, Harrington Allan
机构信息
George Washington School of Medicine, Washington, District of Columbia, USA.
Johns Hopkins School of Medicine, Baltimore, Maryland, USA.
出版信息
J Med Virol. 2021 May;93(5):2588-2590. doi: 10.1002/jmv.26812. Epub 2021 Jan 27.
Abstract
摘要
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本文引用的文献
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Lower-Dose Zinc for Childhood Diarrhea - A Randomized, Multicenter Trial.低剂量锌治疗儿童腹泻：一项随机、多中心试验。
N Engl J Med. 2020 Sep 24;383(13):1231-1241. doi: 10.1056/NEJMoa1915905.
2
COVID-19: Poor outcomes in patients with zinc deficiency.新型冠状病毒肺炎：锌缺乏症患者的不良预后。
Int J Infect Dis. 2020 Nov;100:343-349. doi: 10.1016/j.ijid.2020.09.014. Epub 2020 Sep 10.
3
The Potential Impact of Zinc Supplementation on COVID-19 Pathogenesis.锌补充剂对 COVID-19 发病机制的潜在影响。
Front Immunol. 2020 Jul 10;11:1712. doi: 10.3389/fimmu.2020.01712. eCollection 2020.
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Symptom Duration and Risk Factors for Delayed Return to Usual Health Among Outpatients with COVID-19 in a Multistate Health Care Systems Network - United States, March-June 2020.症状持续时间和多州医疗保健系统网络中 COVID-19 门诊患者恢复健康延迟的风险因素 - 美国，2020 年 3 月至 6 月。
MMWR Morb Mortal Wkly Rep. 2020 Jul 31;69(30):993-998. doi: 10.15585/mmwr.mm6930e1.
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Treatment of SARS-CoV-2 with high dose oral zinc salts: A report on four patients.高剂量口服锌盐治疗 SARS-CoV-2：四例患者报告。
Int J Infect Dis. 2020 Oct;99:307-309. doi: 10.1016/j.ijid.2020.06.006. Epub 2020 Jun 6.
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Zinc lozenges and the common cold: a meta-analysis comparing zinc acetate and zinc gluconate, and the role of zinc dosage.锌含片与普通感冒：一项比较醋酸锌和葡萄糖酸锌以及锌剂量作用的荟萃分析。
JRSM Open. 2017 May 2;8(5):2054270417694291. doi: 10.1177/2054270417694291. eCollection 2017 May.
7
Zn(2+) inhibits coronavirus and arterivirus RNA polymerase activity in vitro and zinc ionophores block the replication of these viruses in cell culture.锌（2+）在体外抑制冠状病毒和动脉病毒 RNA 聚合酶的活性，而锌离子载体则阻断这些病毒在细胞培养中的复制。
PLoS Pathog. 2010 Nov 4;6(11):e1001176. doi: 10.1371/journal.ppat.1001176.
8
Zinc lozenges as cure for the common cold--a review and hypothesis.锌含片治疗普通感冒——综述与假说。
Med Hypotheses. 2010 Mar;74(3):482-92. doi: 10.1016/j.mehy.2009.10.017. Epub 2009 Nov 10.
9
PDTC inhibits picornavirus polyprotein processing and RNA replication by transporting zinc ions into cells.PDTC通过将锌离子转运到细胞中来抑制小核糖核酸病毒多聚蛋白加工和RNA复制。
J Gen Virol. 2007 Apr;88(Pt 4):1206-1217. doi: 10.1099/vir.0.82634-0.
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Zinc supplementation decreases incidence of infections in the elderly: effect of zinc on generation of cytokines and oxidative stress.补充锌可降低老年人感染的发生率：锌对细胞因子生成和氧化应激的影响。
Am J Clin Nutr. 2007 Mar;85(3):837-44. doi: 10.1093/ajcn/85.3.837.
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