King Abdulaziz University Hospital, KSA.
King Fahad Specialist Hospital, Dammam KSA.
Expert Rev Cardiovasc Ther. 2021 Mar;19(3):221-236. doi: 10.1080/14779072.2021.1878878.
Despite the widespread and increasing use of NOACs in Saudi Arabia, there is a lack of contemporary guidance specific to the region. In particular, guidance on NOAC use in high-risk patients who are more likely to experience bleeding with oral anticoagulant therapy is needed. There is an unmet need for a review of contemporary evidence coupled with expert insights on safe and effective NOAC use in high-risk patients with AF in Saudi Arabia.
This article provides a detailed review of contemporary literature on NOAC use in high-risk patients with AF. Additionally, key gaps in the literature are identified and expert insights are shared to guide effective management of patients and the significance of local data is evaluated with respect to challenges in optimizing the use of NOACs.
This article provides information that complements and expands on existing reviews and guidelines on NOAC use in patients with AF, with a focus on challenges specific to the Saudi Arabian context with the potential to make a positive contribution to the medical community in Saudi Arabia and in other nations.
尽管在沙特阿拉伯,NOAC 的应用广泛且不断增加,但针对该地区的现代指南却十分匮乏。特别是,对于更有可能因口服抗凝治疗而出血的高危患者,需要关于 NOAC 使用的指导。沙特阿拉伯的 AF 高危患者中,需要对现代证据进行审查,并结合专家意见,以安全有效的方式使用 NOAC,这方面存在未满足的需求。
本文详细回顾了 AF 高危患者中使用 NOAC 的现代文献。此外,还确定了文献中的关键空白,并分享了专家意见,以指导高危患者的有效管理,同时评估了当地数据的意义,以应对优化 NOAC 使用的挑战。
本文提供的信息补充和扩展了现有的 AF 患者使用 NOAC 的综述和指南,重点关注沙特阿拉伯特定背景下的挑战,有望为沙特阿拉伯和其他国家的医学界做出积极贡献。