State Key Laboratory for Oxo Synthesis and Selective Oxidation, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, P. R. China.
Hefei National Laboratory for Physical Sciences at the Microscale and Department of Chemistry, Center for Excellence in Molecular Synthesis, University of Science and Technology of China, Chinese Academy of Sciences, Hefei 230026, P. R. China.
Org Biomol Chem. 2021 Feb 18;19(6):1274-1277. doi: 10.1039/d0ob02529a.
An approach for the synthesis of quinolizinone with potential bioactivity has been developed via palladium-catalytic dearomative cyclocarbonylation of allyl alcohol. Diverse quinolizinone compounds could be attained with good efficiencies. A feasible reaction pathway could be a successive procedure of allylation, dearomatization, CO insertion and the Heck reaction.
一种具有潜在生物活性的喹啉酮的合成方法已经通过钯催化的烯丙醇去芳构化环羰基化反应开发出来。可以以良好的效率获得多种喹啉酮化合物。一个可行的反应途径可能是连续的烯丙基化、去芳构化、CO 插入和 Heck 反应。
