Stellmacher Florian, Perner Sven
Pathologie, Forschungszentrum Borstel, Leibniz Lungenzentrum, Parkallee 1-40, 23845, Borstel, Deutschland.
Institut für Pathologie, Universität zu Lübeck, Universitätsklinikum Schleswig-Holstein, Lübeck, Deutschland.
Pathologe. 2021 Feb;42(1):64-70. doi: 10.1007/s00292-020-00893-7. Epub 2021 Jan 21.
The spectrum of pulmonary granulomatoses is wide and includes infectious and noninfectious entities, each with very different therapeutic consequences. The first step of histological examination discriminates between necrotizing and non-necrotizing granulomatosis. After this, an infectious cause of the granulomatosis has to be excluded by special histological stains and molecular-pathologic methods, if necessary. Diagnosis also includes clinical, radiological, and microbiological findings. The process of pathological examination should be standardized as described.
肺部肉芽肿病的范围很广,包括感染性和非感染性疾病,每种疾病的治疗结果差异很大。组织学检查的第一步是区分坏死性和非坏死性肉芽肿病。在此之后,如有必要,必须通过特殊的组织学染色和分子病理学方法排除肉芽肿病的感染性病因。诊断还包括临床、放射学和微生物学检查结果。病理检查过程应按所述进行标准化。