Department of Chemistry, Ghent University, Krijgslaan 281-S3, 9000, Ghent, Belgium.
Department of Chemistry, KU Leuven, Celestijnenlaan 200D, 3001, Leuven, Belgium.
Chemistry. 2021 Apr 12;27(21):6479-6488. doi: 10.1002/chem.202004951. Epub 2021 Mar 11.
In recent years, luminescent materials doped with Ln ions have attracted much attention for their application as optical thermometers based on both downshifting and upconversion processes. This study presents research done on the development of highly sensitive optical thermometers in the physiological temperature range based on poly(methyl methacrylate) (PMMA) films doped with two series of visible Ln complexes (Ln =Tb , Eu , and Sm ) and SiO nanoparticles (NPs) coated with these PMMA films. The best performing PMMA film doped with Tb and Eu complexes was the PMMA[TbEuL tppo]1 film (L =4,4,4-trifluoro-1-phenyl-1,3-butadionate; tppo=triphenylphosphine oxide), which showed good temperature sensing of S =4.21 % K at 313 K, whereas for the PMMA films doped with Tb and Sm complexes the best performing was the PMMA[TbSmL tppo]3 film (L =4,4,4-trifluoro-1-(4-chlorophenyl)-1,3-butadionate), with S =3.64 % K at 313 K. Additionally, SiO NPs coated with the best performing films from each of the series of PMMA films (Tb-Eu and Tb-Sm) and their temperature-sensing properties were studied in water, showing excellent performance in the physiological temperature range (PMMA[TbEuL tppo]1@SiO : S =3.84 % °C at 20 °C; PMMA[TbSmL tppo]3@SiO : S =3.27 % °C at 20 °C) and the toxicity of these nanoparticles on human cells was studied, showing that they were nontoxic.
近年来，基于下转换和上转换过程的镧系离子掺杂发光材料因其在光学温度计中的应用而受到广泛关注。本研究旨在开发基于聚甲基丙烯酸甲酯（PMMA）薄膜的高灵敏度光学温度计，该薄膜掺杂了两个系列的可见镧系配合物（Ln =Tb、Eu 和 Sm）和涂覆有这些 PMMA 薄膜的二氧化硅纳米颗粒（NPs）。在掺杂 Tb 和 Eu 配合物的 PMMA 薄膜中，性能最好的是 PMMA[TbEuL tppo]1 薄膜（L =4,4,4-三氟-1-苯基-1,3-丁二酮；tppo=三苯基氧化膦），在 313 K 时，其温度传感性能为 S =4.21 % K；而对于掺杂 Tb 和 Sm 配合物的 PMMA 薄膜，性能最好的是 PMMA[TbSmL tppo]3 薄膜（L =4,4,4-三氟-1-（4-氯苯基）-1,3-丁二酮），在 313 K 时，其温度传感性能为 S =3.64 % K。此外，还研究了涂覆有每个系列 PMMA 薄膜（Tb-Eu 和 Tb-Sm）中性能最好的薄膜的 SiO NPs 的温度传感性能及其在水中的性能，在生理温度范围内表现出优异的性能（PMMA[TbEuL tppo]1@SiO：在 20°C 时 S =3.84 % °C；PMMA[TbSmL tppo]3@SiO：在 20°C 时 S =3.27 % °C），并研究了这些纳米粒子对人体细胞的毒性，结果表明它们是无毒的。
