抗菌药物的最新进展。
Recent advances in antibacterial agents.
机构信息
State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Shanghai 201203, China; University of Chinese Academy of Sciences, No.19(A) Yuquan Road, Beijing 100049, China.
State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Shanghai 201203, China; University of Chinese Academy of Sciences, No.19(A) Yuquan Road, Beijing 100049, China.
出版信息
Bioorg Med Chem Lett. 2021 Mar 1;35:127799. doi: 10.1016/j.bmcl.2021.127799. Epub 2021 Jan 19.
Antimicrobial resistance is a global challenge and the effectiveness of old antibiotics is decreasing. Discovery and development of antibacterial agents have been accelerated to replenish the arsenal of antibiotics which is limited and shrinking. In recent years, significant advances have achieved in the antibacterial area, including new compounds of known classes and new compounds with new mechanisms. This review summarizes these advances and provides perspective on future directions of antibacterial agents.
抗菌药物耐药性是一个全球性挑战，且旧抗生素的有效性正在降低。为了补充有限且不断减少的抗生素储备，人们已经加速了抗菌药物的发现和开发。近年来，在抗菌领域取得了重大进展，包括已知类别中的新型化合物和具有新型作用机制的新型化合物。本综述总结了这些进展，并对未来抗菌药物的发展方向提供了展望。
Zotero 插件