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伴有 COVID-19 病史的阻塞性睡眠呼吸暂停患者自动持续气道正压通气需求的改变。

Alteration of Auto-CPAP requirements in obstructive sleep apnea patients with COVID-19 history.

机构信息

Eskisehir City Hospital, Otorhinolaryngology Dept, Eskisehir, Turkey.

Eskisehir Yunus Emre Hospital, Otorhinolaryngology Dept, Eskisehir, Turkey.

出版信息

Am J Otolaryngol. 2021 May-Jun;42(3):102919. doi: 10.1016/j.amjoto.2021.102919. Epub 2021 Jan 15.

Abstract

BACKGROUND

Coronavirus disease 2019 (COVID-19) is an infectious disease that leads to critical respiratory problems. Obstructive sleep apnea (OSA) is the most common sleep-associated breathing disease and is represented by repetitive experiences of constraint of the respiratory tract prompting to reduced or deficient breathing during sleep. Auto-Continuous positive airway pressure (Auto-CPAP) is a modality of respiratory ventilation used as gold standart in the treatment of OSA.

OBJECTIVE

This study was performed to conclude the alteration of Auto-CPAP levels in OSA patients who had COVID-19 history.

METHODS

Nineteen OSA patients who had cured COVID-19 and used Auto-CPAP were included in this study. Nightly Auto-CPAP 95th percentile pressure (95thpp), median CPAP pressure and AHI before COVID-19 disease and one month after COVID therapy were recorded from electronic cards of Auto-CPAP devices.

RESULTS

Before COVID infection, average Auto-CPAP 95thpp was 8.56 ± 0.17 cm HO. One month after COVID-19, average Auto-CPAP 95thpp was 9.78 ± 0.21 cm HO (P < 0.01). While Median CPAP pressure was 7.49 ± 0.16 cm HO before COVID, it was found to be 8.15 ± 0.19 cm HO after the disease (P < 0.01).

CONCLUSIONS

The increase in need of average Auto-CPAP 95thpp and median CPAP pressure in OSA patients who have had COVID-19 disease and use Auto-CPAP shows that this disease causes problems in both the lower and upper airways.

摘要

背景

2019 年冠状病毒病(COVID-19)是一种导致严重呼吸道问题的传染病。阻塞性睡眠呼吸暂停(OSA)是最常见的与睡眠相关的呼吸疾病,其特征是呼吸道反复受限,导致睡眠期间呼吸减少或不足。自动持续气道正压通气(Auto-CPAP)是一种呼吸通气模式,被用作 OSA 治疗的金标准。

目的

本研究旨在总结患有 COVID-19 病史的 OSA 患者 Auto-CPAP 水平的变化。

方法

本研究纳入了 19 例已治愈 COVID-19 并使用 Auto-CPAP 的 OSA 患者。从 Auto-CPAP 设备的电子卡中记录了 COVID-19 疾病前和 COVID 治疗后一个月的夜间 Auto-CPAP 95 百分位压力(95thpp)、中位 CPAP 压力和 AHI。

结果

COVID 感染前,平均 Auto-CPAP 95thpp 为 8.56±0.17 cm HO。COVID-19 后一个月,平均 Auto-CPAP 95thpp 为 9.78±0.21 cm HO(P<0.01)。COVID 前中位 CPAP 压力为 7.49±0.16 cm HO,COVID 后为 8.15±0.19 cm HO(P<0.01)。

结论

患有 COVID-19 疾病并使用 Auto-CPAP 的 OSA 患者的平均 Auto-CPAP 95thpp 和中位 CPAP 压力需求增加表明,这种疾病会对上、下呼吸道都造成问题。

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