Milgram J W
Department of Orthopaedic Surgery, Northwestern University Medical School, Chicago, IL 60611.
Radiology. 1988 Apr;167(1):155-60. doi: 10.1148/radiology.167.1.3347718.
Sixty-one cases of surgically treated solitary intraosseous lipoma were staged into three categories depending on the degree of involution present histologically: stage 1, tumors of viable fat cells; stage 2, transitional cases composed partly of viable fat cells but also demonstrating fat necrosis and calcification; and stage 3, lesions demonstrating necrotic fat, calcification of necrotic fat, variable degrees of cyst formation, and reactive woven bone formation. Each of these stages had radiologic features that could be correlated with the histopathologic findings in the excised tissue. Examples of stage 3 lesions have frequently been misdiagnosed as unusual bone infarcts or other lesions. Intraosseous lipoma may be a less rare lesion than has previously been suggested.
61例接受手术治疗的孤立性骨内脂肪瘤根据组织学上的 involution 程度分为三类：1期，由存活脂肪细胞构成的肿瘤；2期，部分由存活脂肪细胞组成，但也显示脂肪坏死和钙化的过渡性病例；3期，显示坏死脂肪、坏死脂肪钙化、不同程度囊肿形成以及反应性编织骨形成的病变。这些阶段中的每一个都有与切除组织中的组织病理学发现相关的放射学特征。3期病变的例子经常被误诊为不寻常的骨梗死或其他病变。骨内脂肪瘤可能比以前认为的更为常见。
