Rubin J B, Wright A, Enzmann D R
Department of Diagnostic Radiology, Stanford University Medical Center, CA 94305.
Radiology. 1988 Apr;167(1):225-31. doi: 10.1148/radiology.167.1.3347726.
To determine whether the motion of cerebrospinal fluid (CSF) in the lumbar spine degrades T2-weighted magnetic resonance (MR) images, a spine phantom, three healthy volunteers, and a prospective series of 20 patients suspected of having lumbar spine disease underwent MR imaging with and without motion-compensation techniques. In the phantom, pulsation amplitudes as low as 3 mm (within the physiologic range of human lumbar CSF motion) reduced image quality on conventional images but not on motion-compensated images. Similar findings were observed in two volunteers and 11 patients. The magnitude of the artifacts was variable; they could impair visualization of the conus, decrease contrast or reduce the sharpness of the CSF-thecal sac interface, and cause focal regions of reduced CSF signal intensity adjacent to bulging disks. Image quality was most improved when peripheral gating was combined with even-echo rephasing. In the patient group, the use of motion-compensation techniques increased the CSF signal-to-noise ratio by an average of 29% (P less than .01); this resulted in improved contrast between the conus and extradural structures. The data suggest that CSF motion compensation is clinically useful during T2-weighted MR imaging of the lumbar spine.
为了确定腰椎中脑脊液（CSF）的流动是否会降低T2加权磁共振（MR）图像的质量，对一个脊柱模型、三名健康志愿者以及一系列20例疑似患有腰椎疾病的患者进行了前瞻性研究，分别在使用和不使用运动补偿技术的情况下进行MR成像。在模型中，低至3毫米的脉动幅度（在人类腰椎CSF运动的生理范围内）会降低传统图像的质量，但不会降低运动补偿图像的质量。在两名志愿者和11例患者中也观察到了类似的结果。伪影的程度各不相同；它们可能会妨碍对圆锥的观察，降低对比度或降低CSF-硬脊膜囊界面的清晰度，并在膨出椎间盘附近导致CSF信号强度降低的局部区域。当外周门控与偶数回波重聚相结合时，图像质量改善最为明显。在患者组中，使用运动补偿技术使CSF信噪比平均提高了29%（P小于0.01）；这使得圆锥与硬膜外结构之间的对比度得到改善。数据表明，在腰椎的T2加权MR成像过程中，CSF运动补偿在临床上是有用的。
