Ecological and Biological Sciences Department (DEB), University of Tuscia, Via S. Camillo de Lellis snc, 01100 Viterbo, Italy.
Laboratorio de Estudios Cristalográficos, Instituto Andaluz de Ciencias de la Tierra, Consejo Superior de Investigaciones Científicas-Universidad de Granada, Avenida de las Palmeras 4, Armilla, 18100 Granada, Spain.
Int J Mol Sci. 2021 Jan 18;22(2):917. doi: 10.3390/ijms22020917.
The goal of prebiotic chemistry is the depiction of molecular evolution events preceding the emergence of life on Earth or elsewhere in the cosmos. Plausible experimental models require geochemical scenarios and robust chemistry. Today we know that the chemical and physical conditions for life to flourish on Earth were at work much earlier than thought, i.e., earlier than 4.4 billion years ago. In recent years, a geochemical model for the first five hundred million years of the history of our planet has been devised that would work as a cradle for life. Serpentinization processes in the Hadean eon affording self-assembled structures and vesicles provides the link between the catalytic properties of the inorganic environment and the impressive chemical potential of formamide to produce complete panels of organic molecules relevant in pre-genetic and pre-metabolic processes. Based on an interdisciplinary approach, we propose basic transformations connecting geochemistry to the chemistry of formamide, and we hint at the possible extension of this perspective to other worlds.
前生物化学的目标是描述地球或宇宙其他地方生命出现之前的分子进化事件。合理的实验模型需要地球化学情景和强大的化学。今天我们知道，生命在地球上繁荣的化学和物理条件比我们想象的要早得多，也就是说，比 44 亿年前更早。近年来，人们设计了一个地球历史最初 5 亿年的地球化学模型，它可以作为生命的摇篮。冥古宙时期的蛇纹石化过程提供了自组装结构和小泡，将无机环境的催化特性与甲酰胺的惊人化学势联系起来，从而产生与前遗传和前代谢过程相关的完整有机分子面板。基于跨学科的方法，我们提出了将地球化学与甲酰胺化学联系起来的基本转化，并暗示了这种观点可能扩展到其他世界。
