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[磁共振成像在梗死所致水平性眼球运动麻痹中的应用]

[Magnetic resonance imaging in horizontal oculomotor paralysis caused by infarction].

作者信息

Hommel M, Besson G, Tarel V, Gaio J M, Pollak P, Borgel F, Le Bas J F, Perret J

机构信息

Clinique Neurologique, C.H.U. Grenoble.

出版信息

Rev Neurol (Paris). 1988;144(1):18-24.

PMID:3347805
Abstract

Four patients with focal brainstem ischemic strokes and various types of horizontal oculomotor disturbances have been studied clinically and radiologically. One had a six nerve palsy, one a unilateral internuclear ophthalmoplegia, one a Fisher's one-and-a-half syndrome, and one a paramedian pontine reticular formation syndrome with a sixth nerve palsy. In all patients a C.T. Scan and a Magnetic Resonance Imaging (MRI) were obtained. The MRI study was performed on a CGR Magniscan 5000 with a superconducting magnet of 0.5 Tesla. In all patients a hypersignal in T2 weighted images was shown and corresponded to the brainstem infarct. MRI allowed accurate delineation of the lesion and clinico-radiologic correlations in three patients. But the low specificity of MRI does not permit to distinguish edema from necrosis, gliosis or demyelination in a region with a pathological MRI signal. In one patient this low specificity and perhaps partial volume effects decreased the accuracy of the clinico-topographic correlation.

摘要

对4例患有局灶性脑干缺血性中风及各种类型水平眼球运动障碍的患者进行了临床和影像学研究。1例有第六神经麻痹,1例有单侧核间性眼肌麻痹,1例有费希尔(Fisher)半侧综合征,1例有伴有第六神经麻痹的脑桥旁正中网状结构综合征。所有患者均进行了CT扫描和磁共振成像(MRI)检查。MRI检查使用的是CGR Magniscan 5000,配备0.5特斯拉的超导磁体。所有患者在T2加权图像上均显示高信号,对应于脑干梗死。MRI能够准确勾勒出3例患者病变的轮廓,并进行临床与影像学的相关性分析。但MRI的低特异性使得在具有病理性MRI信号的区域无法区分水肿与坏死、胶质增生或脱髓鞘。在1例患者中,这种低特异性以及可能的部分容积效应降低了临床与地形学相关性分析的准确性。

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