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[老年功能康复单元入院时基线衰弱和握力对出院结局的预测能力]

[Predictive ability of baseline frailty and handgrip strength at admission on outcomes at discharge in a geriatric functional recovery unit].

作者信息

Madruga-Flores María, Gómez-Del Río Rocío, Delgado-Domínguez Luz, Martínez-Zujeros Sergio, Pallardo-Rodil Beatriz, Baztán-Cortés Juan José

机构信息

Servicio de Geriatría, Hospital Central de la Cruz Roja San José y Santa Adela, Madrid, España.

Servicio de Geriatría, Hospital Central de la Cruz Roja San José y Santa Adela, Madrid, España.

出版信息

Rev Esp Geriatr Gerontol. 2021 Mar-Apr;56(2):91-95. doi: 10.1016/j.regg.2020.12.002. Epub 2021 Jan 19.

Abstract

OBJECTIVE

To evaluate the predictive capacity of different frailty scales, as well as the strength of the handgrip, and to determine their relationship with clinical favourable outcomes.

PATIENTS AND METHOD

Prospective study of patients admitted to the Geriatric Functional Recovery Unit (GFRU) of the Hospital Central Cruz Roja. The «FRAIL» scale, «Clinical Frailty Scale» (CFS) and «Fragil-VIG» index, and handgrip strength by hydraulic dynamometer were completed on admission. A functional gain was assumed as 20 or more points in the Barthel Index and return to home, as good outcomes at discharge. The discriminative capacity of favourable outcomes for each frailty scale and handgrip strength was analysed by means of ROC curves, calculating the C statistic (area under the curve = AUC).

RESULTS

The analysis included 74 patients (median age 82 years; 48.5% women), admitted for stroke recovery (65%), orthopaedic pathology (16%), and other causes (19%). The prevalence of frailty varied between 31% (FRAIL scale), 40% (CFS), and 57.5% («Fragil-VIG»). Median handgrip strength was 15 Kg in males (interquartile range 11-21), and 9 Kg in females (interquartile range 7-12). At discharge, 51.5% of patients had a functional gain of 20 or more points in Barthel index, and 63% returned to their previous home. The discriminating ability to achieve acceptable functional gain at discharge was good for CFS (AUC = 0.72; 95% CI; 0.60-0.84) and «Fragil-VIG» (AUC = 0.72; 95% CI;0.58-0.82), and handgrip strength was the only tool related to return home (AUC = 0.68; 95% CI;0.56-0.81).

CONCLUSION

To evaluate frailty on admission to a GFRU contributes to predicting favourable clinical outcomes, but the discriminating capacity of each scale is variable.

摘要

目的

评估不同衰弱量表以及握力的预测能力,并确定它们与临床良好结局的关系。

患者与方法

对中央红十字医院老年功能康复科收治的患者进行前瞻性研究。入院时完成“FRAIL”量表、“临床衰弱量表”(CFS)和“Fragil-VIG”指数评估,并用液压测力计测量握力。以Barthel指数增加20分及以上且出院后回家作为良好结局。通过ROC曲线分析各衰弱量表和握力对良好结局的判别能力,计算C统计量(曲线下面积=AUC)。

结果

分析纳入74例患者(中位年龄82岁;48.5%为女性),因中风康复入院者占65%,因骨科疾病入院者占16%,因其他原因入院者占19%。衰弱患病率在“FRAIL”量表为31%、CFS为40%、“Fragil-VIG”为57.5%之间。男性握力中位数为15千克(四分位间距11-21),女性为9千克(四分位间距7-12)。出院时,51.5%的患者Barthel指数增加20分及以上,63%的患者出院后回家。CFS(AUC = 0.72;95%CI;0.60-0.84)和“Fragil-VIG”(AUC = 0.72;95%CI;0.58-0.82)对出院时获得可接受功能改善的判别能力良好,握力是与回家相关的唯一工具(AUC = 0.68;95%CI;0.56-0.81)。

结论

评估老年功能康复科入院时的衰弱情况有助于预测良好的临床结局,但各量表的判别能力各不相同。

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