Liddell Charly, Plantier Françoise
Laboratoire d'anatomie pathologique, centre hospitalier de La Roche-sur-Yon, boulevard Stephane-Moreau, 85000 La Roche-sur-Yon, France.
Laboratoire d'anatomie pathologique, hôpital Cochin, Paris, France.
Ann Pathol. 2022 Jan;42(1):85-88. doi: 10.1016/j.annpat.2020.12.006. Epub 2021 Jan 19.
We report a case of a vulvar verruciform xanthoma. Verruciform xanthoma is a rare benign lesion that occurs most commonly on the oral and genital mucosa. Under the microscope, this lesion displays acanthotic papillary epidermis with parakeratosis that extends deep into the epithelium, elongated rete ridges and xanthomatous cells in the papillary dermis. Vulvar lesions almost always occur in a local pathological context (lichen planus or sclerosus). It is important to be aware of this entity as it can mimic squamous carcinoma.
我们报告一例外阴疣状黄瘤病例。疣状黄瘤是一种罕见的良性病变,最常发生于口腔和生殖器黏膜。在显微镜下,该病变表现为棘层肥厚的乳头样表皮伴角化不全,其深入上皮深层,真皮乳头层有延长的 rete 嵴和黄瘤细胞。外阴病变几乎总是发生在局部病理背景下(扁平苔藓或硬化症)。认识到这一实体很重要,因为它可能会模仿鳞状细胞癌。