Tunis Med. 2020 Dec;98(12):1031-1038.
Obstructive Sleep Apnea Syndrome (OSAS) is a common but often under diagnosed condition that constitutes a real public health problem. The prevalence of OSAS in atrial fibrillation (AF) patients ranges from 32 to 85% according to recent studies.
To determine the prevalence and severity of OSAS in a population followed for non-valvular AF (NVAF), and to identify OSAS's predictive factors in this population.
A cross-sectional study was conducted, including successive patients followed for NVAF. Patients with a known history of OSAS were not included. All patients had a clinical screening for symptoms suggestive of OSAS and underwent an ambulatory sleep study.
We included 100 patients in this study. OSAS was detected in 90% of NVAF patients. The average apnea-hypopnea index (AHI) was 21.6 ± 13.6 e/h. OSAS was mild in 32%, moderate in 27% and severe in 31% of cases. Clinical characteristics were comparable between patients with and without OSAS. The multivariate analytical study concluded that independent predictive factors of OSAS in AF patients were an age greater than 61 years (p=0.029), AF duration more than 2 years (p=0.04) and snoring (p=0.01).
OSAS was diagnosed in 90% of NVAF patients. Thus, a systematic screening for OSAS in AF patients may be a relevant approach given its high prevalence in this population and its therapeutic implications. Snoring, age greater than 61 years, and AF duration more than 2 years were independently associated with OSAS in our study.
阻塞性睡眠呼吸暂停综合征(OSAS)是一种常见但常被漏诊的疾病,构成了真正的公共卫生问题。根据最近的研究,OSAS 在心房颤动(AF)患者中的患病率为 32%至 85%。
确定非瓣膜性心房颤动(NVAF)患者中 OSAS 的患病率和严重程度,并确定该人群中 OSAS 的预测因素。
进行了一项横断面研究,包括连续随访 NVAF 的患者。不包括已知 OSAS 病史的患者。所有患者均进行了 OSAS 症状临床筛查,并进行了睡眠监测。
本研究共纳入 100 例患者。90%的 NVAF 患者检测到 OSAS。平均呼吸暂停低通气指数(AHI)为 21.6±13.6 e/h。OSAS 轻度占 32%,中度占 27%,重度占 31%。有和无 OSAS 的患者临床特征无差异。多变量分析研究得出结论,AF 患者 OSAS 的独立预测因素为年龄大于 61 岁(p=0.029)、AF 持续时间大于 2 年(p=0.04)和打鼾(p=0.01)。
90%的 NVAF 患者诊断为 OSAS。因此,鉴于 AF 患者 OSAS 的高患病率及其治疗意义,对 AF 患者进行系统性 OSAS 筛查可能是一种有效的方法。在我们的研究中,打鼾、年龄大于 61 岁和 AF 持续时间大于 2 年与 OSAS 独立相关。