Petrovichev N N, Annamukhammedov A, Zatsepin S T, Lipkin S I, Dvorova E K
Vopr Onkol. 1988;34(2):157-62.
A retrospective study of 42 patients with bone fibrosarcoma was carried out. A new highly informative index--tumor growth rate--is suggested. It is a ratio of tumor maximum diameter to case history length (Rtg = L, CM/t, month). Three histologically-identified grades of fibrosarcoma malignity are discussed. They are based on the variation in metastasis development and survival rates. As a result of mathematical treatment of the findings, 8 characteristics of bone fibrosarcoma were identified which influenced prognosis. A multi-factorial analysis of the data was undertaken using said characteristics. Indexes were calculated for each characteristic and tabulated to prognosticate 3-year survival of patients with fibrosarcoma of the bone.
对42例骨纤维肉瘤患者进行了回顾性研究。提出了一个新的高信息量指标——肿瘤生长率。它是肿瘤最大直径与病程长度的比值(Rtg = L,厘米/t,月)。讨论了组织学确定的三种纤维肉瘤恶性程度分级。它们基于转移发展和生存率的变化。对研究结果进行数学处理后,确定了影响骨纤维肉瘤预后的8个特征。使用这些特征对数据进行了多因素分析。计算了每个特征的指标并制成表格,以预测骨纤维肉瘤患者的3年生存率。