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调节妊娠期糖尿病的营养素:队列研究的系统评价 2019 年 1 月至 2020 年 1 月。

Nutrients that modulate gestational diabetes mellitus: A systematic review of cohort studies Jan 2019-Jan 2020.

机构信息

Department of Obstetrics and Gynaecology, Accredited Endometriosis Centre, Northwick Park Hospital, London North West Healthcare NHS Trust, Harrow, London, UK.

Pharmacy Department, University of Athens, Panepistimiopolis of Zographou, Athens, Greece.

出版信息

Int J Clin Pract. 2021 Aug;75(8):e14033. doi: 10.1111/ijcp.14033. Epub 2021 Mar 5.

Abstract

BACKGROUND

The role of eating habits of pregnant women in the development and treatment of gestational diabetes mellitus (GDM) is well established.

OBJECTIVES

To estimate the contribution of specific nutrients and dietary patterns in the development or privation of GDM in pregnant women.

DATA SOURCES

A systematic review of cohort studies, published between January 2019 and January 2020, of English articles using PubMed, Scopus and Europe PMC databases. Search terms included diabetes, pregnancy, dietary, food, and nutrients.

STUDY SELECTION

Only cohort studies about the association between eating habits before and during pregnancy and the risk of GDM in English were included. The studies used dietary patterns, specific nutrients or records of food intake of the participants using a questionnaire.

DATA EXTRACTION

Two authors independently extracted data from articles-including dietary patterns, food intake, nutrients, number and demographic data of participants, data about pregnancies-using predefined criteria.

RESULTS

In total, 28 cohort studies were organised to examine the correlation between dietary patterns and the prevention of GDM. Studies were conducted in 13 countries and included 3 058 242 participants. Of those, 13 (46%) studies focused on the consumption of vitamins, probiotics, micronutrients, folate, vegetables and fruits. Moreover, seven (25%) studies focused on what is considered to be "unhealthy" eating habits, including prudent and Western dietary patterns. The mediterranean pattern was used in three (11%) studies.

CONCLUSIONS

Ongoing studies support advice to adhere to a healthy balanced diet, with the addition of folic acid and a multi-vitamin suitable for pregnancy. There is new evidence suggesting probiotics and cod-liver oil supplementation may improve glycaemic control and also the important consideration of the psychological influences of eating.

摘要

背景

孕妇饮食习惯在妊娠糖尿病(GDM)的发生和治疗中的作用已得到充分证实。

目的

评估特定营养素和饮食模式在孕妇 GDM 发生或缺乏中的作用。

资料来源

使用 PubMed、Scopus 和 Europe PMC 数据库,对 2019 年 1 月至 2020 年 1 月期间发表的英文队列研究进行了系统综述。检索词包括糖尿病、妊娠、饮食、食物和营养。

研究选择

仅纳入关于孕前和孕期饮食习惯与 GDM 风险之间关联的英文队列研究。这些研究使用了饮食模式、特定营养素或参与者使用问卷记录的食物摄入量。

资料提取

两位作者独立地从文章中提取数据,包括饮食模式、食物摄入量、营养素、参与者的数量和人口统计学数据、与妊娠相关的数据,使用预定义的标准。

结果

共组织了 28 项队列研究来检验饮食模式与 GDM 预防之间的相关性。这些研究在 13 个国家进行,共纳入 3058242 名参与者。其中,13 项(46%)研究关注维生素、益生菌、微量营养素、叶酸、蔬菜和水果的摄入。此外,7 项(25%)研究关注被认为是“不健康”的饮食习惯,包括谨慎和西方饮食模式。3 项(11%)研究采用了地中海饮食模式。

结论

正在进行的研究支持建议遵循健康均衡的饮食,同时补充叶酸和适合妊娠的多种维生素。有新的证据表明益生菌和鱼肝油补充剂可能改善血糖控制,以及饮食的心理影响这一重要考虑因素。

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