Department of Otorhinolaryngology-Head and Neck Surgery, National Medical Center, Seoul, Republic of Korea.
Department of Otorhinolaryngology, Eulji University Hospital, Eulji University School of Medicine, Republic of Korea.
Am J Otolaryngol. 2021 May-Jun;42(3):102389. doi: 10.1016/j.amjoto.2020.102389. Epub 2020 Jan 3.
The efficacy of nasal septal splints, which are used as alternatives to nasal packs for preventing complications such as synechia and maintaining septal stability after septoplasty, remains controversial. The present meta-analysis assessed the efficacy and safety of nasal septal splints used after septoplasty.
PubMed and Google Scholar databases were systematically searched until June 20, 2019. Randomized controlled trials or cohort or case-control studies comparing patients who received nasal septal splints with those who did not receive splints after septoplasty were included. Primary outcomes included postoperative pain, infection, bleeding, hematoma formation, synechia, and perforation. Random effects models were used to calculate risk differences and risk ratios with 95% confidence intervals (CIs).
Thirty-three eligible studies were included. The estimated rate of synechia was significantly lower in the splint group (0.037, 95% CI 0.024-0.056) than in the no splint group (0.087, 95% CI 0.055-0.135; P = 0.003), while visual analog scale scores for pain and the estimated rates of infection, bleeding, hematoma, and perforation were comparable between groups.
These findings suggest that the use of nasal septal splints as alternatives or in addition to nasal packing prevent synechia after septoplasty without increasing other complications, including pain, thus adding to evidence supporting the use of septal splints, particularly in cases where postoperative synechia is expected.
鼻中隔夹板作为鼻中隔成形术后预防粘连和维持鼻中隔稳定性的替代鼻腔填塞物,其疗效仍存在争议。本荟萃分析评估了鼻中隔成形术后使用鼻中隔夹板的疗效和安全性。
系统检索了 PubMed 和 Google Scholar 数据库,检索时间截至 2019 年 6 月 20 日。纳入比较鼻中隔成形术后使用鼻中隔夹板与未使用夹板患者的随机对照试验或队列或病例对照研究。主要结局包括术后疼痛、感染、出血、血肿形成、粘连和穿孔。使用随机效应模型计算风险差异和风险比及其 95%置信区间(CI)。
纳入 33 项符合条件的研究。与未使用夹板组(0.087,95%CI 0.055-0.135;P=0.003)相比,夹板组的粘连发生率显著较低(0.037,95%CI 0.024-0.056),而疼痛视觉模拟评分和感染、出血、血肿和穿孔的发生率在两组之间无差异。
这些发现表明,鼻中隔夹板的使用可作为鼻中隔成形术后替代鼻腔填塞或附加鼻腔填塞物,预防粘连形成,且不会增加其他并发症,包括疼痛,从而为使用鼻中隔夹板提供了更多的证据支持,特别是在预计术后发生粘连的情况下。