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鼻中隔成形术后不可吸收鼻腔填塞是必要的吗?一项荟萃分析。

Is nonabsorbable nasal packing after septoplasty essential? A meta-analysis.

作者信息

Kim Jong Seung, Kwon Sam Hyun

机构信息

Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, Chonbuk National University, Jeonju, Korea.

Research Institute of Clinical Medicine of Chonbuk National University, Biomedical Research Institute of Chonbuk National University Hospital, Jeonju, Republic of Korea.

出版信息

Laryngoscope. 2017 May;127(5):1026-1031. doi: 10.1002/lary.26436. Epub 2016 Nov 30.

Abstract

OBJECTIVES

Septoplasty is one of the most frequently performed rhinologic surgeries. Complications include nasal bleeding, pain, headache, septal hematoma, synechia, infection, residual septal deviation, and septal perforation. In this study, we aimed to compare complication rates among patients according to packing method.

METHODS

We performed a literature search using PubMed, Embase, and the Cochrane Library through August 2016. Our systematic review followed Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines. Random effect models were used to calculate risk differences and risk ratio with 95% confidence intervals (CIs). Cases referred to the nonpacking group included patients treated with transseptal sutures or septal splints. Cases referred to as the packing group included patients treated with nonabsorbable packing such as Merocel or gauze.

RESULTS

Our search included 20 randomized controlled trials (RCTs) with a total of 1,321 subjects in the nonpacking group and 1,247 subjects in the packing group. There were no significant differences between packing methods regarding bleeding, hematoma, perforation, infection, and residual septal deviation. The risk differences of postoperative pain, headache, and postoperative synechia were -0.50 [95% CI: -0.93 to -0.07, P = .02], -0.42 [95% CI: -0.66 to -0.19, P = .0004], and -0.03 [95% CI: -0.06 to -0.01, P = .01], respectively.

CONCLUSIONS

Nonabsorbable nasal packing is no more effective than treatments without packing after septoplasty. Septal splints and transseptal sutures reduce postoperative pain, headache, and synechia.

LEVEL OF EVIDENCE

1B Laryngoscope, 127:1026-1031, 2017.

摘要

目的

鼻中隔成形术是最常施行的鼻科手术之一。并发症包括鼻出血、疼痛、头痛、鼻中隔血肿、粘连、感染、残余鼻中隔偏曲和鼻中隔穿孔。在本研究中,我们旨在根据填塞方法比较患者之间的并发症发生率。

方法

我们通过2016年8月前使用PubMed、Embase和Cochrane图书馆进行文献检索。我们的系统评价遵循系统评价和Meta分析的首选报告项目指南。采用随机效应模型计算风险差异和风险比,并给出95%置信区间(CI)。归入非填塞组的病例包括接受经鼻中隔缝合或鼻中隔夹板治疗的患者。归入填塞组的病例包括接受诸如Merocel或纱布等不可吸收填塞物治疗的患者。

结果

我们的检索纳入了20项随机对照试验(RCT),非填塞组共有1321名受试者,填塞组有1247名受试者。在出血、血肿、穿孔、感染和残余鼻中隔偏曲方面,填塞方法之间无显著差异。术后疼痛、头痛和术后粘连的风险差异分别为-0.50 [95% CI:-0.93至-0.07,P = .02]、-0.42 [95% CI:-0.66至-0.19,P = .0004]和-0.03 [95% CI:-0.06至-0.01,P = .01]。

结论

鼻中隔成形术后,不可吸收鼻腔填塞并不比不填塞治疗更有效。鼻中隔夹板和经鼻中隔缝合可减轻术后疼痛、头痛和粘连。

证据级别

1B 《喉镜》,127:1026 - 1031,2017年。

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