在危重症新冠-19患者中，使用兰地洛尔控制房颤心率是安全的。 - Suppr

Rate control in atrial fibrillation using Landiolol is safe in critically ill Covid-19 patients.

作者信息

Hariri Geoffroy, Urbina Tomas, Mazerand Sandie, Bige Naike, Baudel Jean-Luc, Ait-Oufella Hafid

机构信息

Service de réanimation médicale, Assistance Publique - Hôpitaux de Paris (AP-HP), Hôpital Saint-Antoine, 184 Rue du Faubourg Saint-Antoine, 75571, Paris Cedex 12, France.

Sorbonne Université, Paris, France.

出版信息

Crit Care. 2021 Jan 22;25(1):33. doi: 10.1186/s13054-021-03470-3.

DOI:10.1186/s13054-021-03470-3

PMID:33482867

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7820818/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c28a/7821545/914e7ac80f1b/13054_2021_3470_Fig1_HTML.jpg

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Rate control in atrial fibrillation using Landiolol is safe in critically ill Covid-19 patients.在危重症新冠-19患者中，使用兰地洛尔控制房颤心率是安全的。

Crit Care. 2021 Jan 22;25(1):33. doi: 10.1186/s13054-021-03470-3.

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Effect of landiolol hydrochloride, an ultra-short-acting beta 1-selective blocker, on supraventricular tachycardia, atrial fibrillation and flutter after pulmonary resection.盐酸拉贝洛尔对肺切除术后室上性心动过速、心房颤动和扑动的影响。

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A prospective observational survey on landiolol in atrial fibrillation/atrial flutter patients with chronic heart failure - AF-CHF landiolol survey.一项关于慢性心力衰竭合并心房颤动/心房扑动患者应用拉地洛尔的前瞻性观察性研究 - AF-CHF 拉地洛尔调查。

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Landiolol: A Review in Tachyarrhythmias.兰地洛尔：治疗快速性心律失常。

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Microcirculatory effects of landiolol: a double-blind, randomised, controlled study after cardiac surgery.兰地洛尔对微循环的影响：一项心脏手术后的双盲、随机、对照研究。

Br J Anaesth. 2021 Jun;126(6):e212-e214. doi: 10.1016/j.bja.2021.03.013. Epub 2021 Apr 24.

Design of a prospective observational survey on landiolol in atrial fibrillation/atrial flutter patients with chronic heart failure - AF-CHF landiolol survey.一项关于兰地洛尔用于慢性心力衰竭合并心房颤动/心房扑动患者的前瞻性观察性研究设计——AF-CHF兰地洛尔研究

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Safety and efficacy of landiolol hydrochloride for prevention of atrial fibrillation after cardiac surgery in patients with left ventricular dysfunction: Prevention of Atrial Fibrillation After Cardiac Surgery With Landiolol Hydrochloride for Left Ventricular Dysfunction (PLATON) trial.盐酸拉贝洛尔预防左心功能障碍患者心脏手术后心房颤动的安全性和有效性：盐酸拉贝洛尔预防左心室功能障碍心脏手术后心房颤动（PLATON）试验。

J Thorac Cardiovasc Surg. 2015 Oct;150(4):957-64. doi: 10.1016/j.jtcvs.2015.07.003. Epub 2015 Jul 10.

Efficacy and Safety of Landiolol Compared to Amiodarone for the Management of Postoperative Atrial Fibrillation in Intensive Care Patients.在重症监护患者中，与胺碘酮相比，兰地洛尔用于治疗术后房颤的疗效和安全性。

J Cardiothorac Vasc Anesth. 2016 Apr;30(2):418-22. doi: 10.1053/j.jvca.2015.09.007. Epub 2015 Sep 25.

Efficacy of landiolol hydrochloride for prevention of atrial fibrillation after heart valve surgery.盐酸兰地洛尔预防心脏瓣膜置换术后房颤的疗效

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Intravenous Landiolol for Rate Control in Supraventricular Tachyarrhythmias in Patients with Left Ventricular Dysfunction: A Systematic Review and Meta-Analysis.静脉注射兰地洛尔对左心室功能不全患者室上性快速心律失常的心率控制：一项系统评价和荟萃分析。

J Clin Med. 2024 Mar 14;13(6):1683. doi: 10.3390/jcm13061683.

Benefits and safety of landiolol for rapid rate control in patients with atrial tachyarrhythmias and acute decompensated heart failure.兰地洛尔用于心房快速性心律失常和急性失代偿性心力衰竭患者快速控制心率的疗效与安全性。

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本文引用的文献

Evaluating the Therapeutic Efficacy and Safety of Landiolol Hydrochloride for Management of Arrhythmia in Critical Settings: Review of the Literature.评估盐酸兰地洛尔在危急情况下治疗心律失常的疗效和安全性：文献综述

Vasc Health Risk Manag. 2020 Apr 3;16:111-123. doi: 10.2147/VHRM.S210561. eCollection 2020.

Efficacy and safety of landiolol, an ultra-short-acting β1-selective antagonist, for treatment of sepsis-related tachyarrhythmia (J-Land 3S): a multicentre, open-label, randomised controlled trial.兰地洛尔治疗脓毒症相关快速性心律失常的疗效和安全性（J-Land 3S）：一项多中心、开放标签、随机对照试验。

Lancet Respir Med. 2020 Sep;8(9):863-872. doi: 10.1016/S2213-2600(20)30037-0. Epub 2020 Mar 31.

Atrial Fibrillation in Patients with Septic Shock: A One-Year Observational Pilot Study.感染性休克患者的心房颤动：一项为期一年的观察性初步研究。

Turk J Anaesthesiol Reanim. 2019 Jun;47(3):213-219. doi: 10.5152/TJAR.2019.44789. Epub 2019 Jan 24.

Adverse cardiac events during catecholamine vasopressor therapy: a prospective observational study.儿茶酚胺血管加压素治疗期间的心脏不良事件：一项前瞻性观察研究。

Intensive Care Med. 2012 Jun;38(6):950-8. doi: 10.1007/s00134-012-2531-2. Epub 2012 Apr 12.

Incidence and prognostic impact of new-onset atrial fibrillation in patients with septic shock: a prospective observational study.新发心房颤动在感染性休克患者中的发生率和预后影响：一项前瞻性观察研究。

Crit Care. 2010;14(3):R108. doi: 10.1186/cc9057. Epub 2010 Jun 10.

In rabbits, landiolol, a new ultra-short-acting beta-blocker, exerts a more potent negative chronotropic effect and less effect on blood pressure than esmolol.在兔子身上，新型超短效β受体阻滞剂兰地洛尔比艾司洛尔具有更强的负性变时作用，而对血压的影响较小。

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Rate control in atrial fibrillation using Landiolol is safe in critically ill Covid-19 patients.

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