Lacey Alexandra M, Rogers Charlotte, Endorf Frederick W, Fey Ryan M, Gayken Jon R, Schmitz Kyle R, Punjabi Gopal V, Whitley Angela B, Masters Thomas C, Moore Johanna C, Nygaard Rachel M
Hennepin Healthcare Medical Center, Minneapolis, Minnesota.
J Burn Care Res. 2021 Aug 4;42(4):817-820. doi: 10.1093/jbcr/irab008.
The treatment of severe frostbite injury has undergone rapid development in the past 30 years with many different diagnostic and treatment options now available. However, there is currently no consensus on the best method for management of this disease process. At our institution, we have designed a protocol for severe frostbite injury that includes diagnosis, medical treatment, wound cares, therapy, and surgery. This study assess the efficacy of our treatment since its implementation six years ago. During this time, all patients with severe frostbite injury were included in prospective observational trial of the protocol. We found that this protocol results in significant tissue salvage with over 80.7% of previously ischemic tissue becoming viable and not requiring amputation. We also were able to improve our center's efficiency over the course of six years and now our current average time from rapid rewarming to delivery of thrombolytics is under six hours.
在过去30年里,严重冻伤的治疗取得了迅速发展,现在有许多不同的诊断和治疗选择。然而,目前对于这种疾病过程的最佳管理方法尚无共识。在我们机构,我们设计了一个针对严重冻伤的方案,包括诊断、药物治疗、伤口护理、治疗和手术。本研究评估了自六年前实施该方案以来的治疗效果。在此期间,所有严重冻伤患者都被纳入该方案的前瞻性观察试验。我们发现,该方案能显著挽救组织,超过80.7%以前缺血的组织恢复活力,无需截肢。我们还在六年的时间里提高了我们中心的效率,现在从快速复温到使用溶栓剂的当前平均时间在六小时以内。