Zhang Dongao, Fan Wayne, Zhao Xingang, Massicotte Eric M, Fan Tao
Spine Center, Sanbo Brain Hospital, Capital Medical University, Beijing, People's Republic of China.
Faculty of Science, University of British Columbia, Canada.
Int J Surg Case Rep. 2021 Feb;79:234-238. doi: 10.1016/j.ijscr.2021.01.035. Epub 2021 Jan 15.
Long-level intramedullary astrocytomas complicated with spine scoliosis are rare. Surgical treatment of such tumors becomes more complicated and challenging when spinal scoliosis is present. However, studies describing the treatment of long segmental intramedullary spinal cord astrocytomas complicated with severe spine scoliosis have been rarely reported.
Two cases of long-level intramedullary astrocytomas complicated with severe spine scoliosis were surgically treated with one-stage operation of tumor resection and scoliosis correction in this report. Case 1: A 16-year-old boy presented to our hospital with a five-month progressive paresthesia, weakness of the left lower limb, and a long-time abnormal body appearance. MRI showed a T4-T12 intramedullary tumor combined with spinal scoliosis. Case 2: A 14-year-old boy presented at our service with a 6-year history of visible spine scoliosis and a 1-year progressive motor disability of bilateral lower limbs. Spine MRI indicated a long-level abnormal syringomyelia signal from C4 to L1 and there was irregular enhancement after intravenous contrast medium administration at C7-T2 and T9-T12 level.
We performed a laminectomy over the whole length of the tumor and corrected the scoliosis with trans-pedicle screws. The patients exhibited a long-time tumor free with largely neurological function preservation. One-stage operation did not generate severe short- or long-term complications. The correction of the scoliosis prevented the progression of the spinal deformity and facilitated the recovery of normal life.
This case report demonstrates that the one-stage resection of long-level intramedullary astrocytoma and correction of the complicated scoliosis might be a feasible option.
长节段髓内星形细胞瘤合并脊柱侧弯较为罕见。当存在脊柱侧弯时,此类肿瘤的手术治疗会变得更加复杂且具有挑战性。然而,关于长节段脊髓髓内星形细胞瘤合并严重脊柱侧弯治疗的研究报道甚少。
本报告中,两例长节段髓内星形细胞瘤合并严重脊柱侧弯的患者接受了肿瘤切除和脊柱侧弯矫正的一期手术治疗。病例1:一名16岁男孩因进行性感觉异常5个月、左下肢无力以及长期身体外观异常前来我院就诊。磁共振成像(MRI)显示T4 - T12节段髓内肿瘤合并脊柱侧弯。病例2:一名14岁男孩因明显脊柱侧弯6年及双侧下肢进行性运动功能障碍1年前来我院就诊。脊柱MRI显示C4至L1节段长节段异常空洞样信号,在C7 - T2和T9 - T12水平静脉注射造影剂后有不规则强化。
我们在肿瘤全长范围进行了椎板切除术,并使用椎弓根螺钉矫正脊柱侧弯。患者长期无瘤生存,神经功能得到了很大程度的保留。一期手术未产生严重的短期或长期并发症。脊柱侧弯的矫正防止了脊柱畸形的进展,并促进了正常生活的恢复。
本病例报告表明,长节段髓内星形细胞瘤的一期切除及复杂脊柱侧弯的矫正可能是一种可行的选择。