Tampa General Hospital, Tampa, Florida.
Gastroenterology and Hepatology, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Clin Gastroenterol Hepatol. 2022 Oct;20(10):2393-2395.e4. doi: 10.1016/j.cgh.2021.01.023. Epub 2021 Jan 21.
First-line treatment for nonalcoholic fatty liver disease (NAFLD) focuses on weight loss through lifestyle modifications. Weight loss ≥5% results in reduction of steatosis and weight loss ≥10% has been associated with improvement in hepatic inflammation and fibrosis. The incidence and sustainability of weight loss among patients with NAFLD were estimated and associating factors identified.
非酒精性脂肪性肝病 (NAFLD) 的一线治疗方法侧重于通过生活方式改变来减轻体重。体重减轻≥5%可导致脂肪变性减少,体重减轻≥10%与肝炎症和纤维化改善相关。估计了 NAFLD 患者的减重发生率和可持续性,并确定了相关因素。