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人群镉暴露及镉毒性干预策略研究进展

A review on Cadmium Exposure in the Population and Intervention Strategies Against Cadmium Toxicity.

机构信息

Key Laboratory of Environmental Medicine Engineering of Ministry of Education, School of Public Health, Southeast University, Nanjing, 210000, Jiangsu, China.

State Key Laboratory of Pollution Control & Resource Reuse, School of the Environment, Nanjing University, Nanjing, 210023, Jiangsu, China.

出版信息

Bull Environ Contam Toxicol. 2021 Jan;106(1):65-74. doi: 10.1007/s00128-020-03088-1. Epub 2021 Jan 23.

Abstract

The rapid industrial development has led to serious cadmium (Cd) pollution. Cd is a toxic heavy metal placing severe health threat to human. Cd can enter the body through the atmosphere, water, soil and food, and has a long half-life (10-30 years), it largely accumulates in kidneys, liver, bone and other organs and causes irreversible damage to the target organs. Cd pollution has also further caused certain carcinogenic and non-carcinogenic health risk. This study summarizes the current situation of Cd pollution, the toxicity of specific target organs, carcinogenic risk and non-carcinogenic risk in the general population, as well as dietary supplements to prevent and mitigate Cd toxication, which aims to focus on the adverse effects of Cd to human from both individual and population perspectives, hoping that not only the health risk of Cd poisoning can be reduced, but also the accurate prevention and control of Cd poisoning can be achieved in the future.

摘要

快速的工业化发展导致了严重的镉(Cd)污染。镉是一种有毒重金属,对人类健康构成严重威胁。镉可以通过大气、水、土壤和食物进入人体,半衰期长(10-30 年),大量积聚在肾脏、肝脏、骨骼等器官,对靶器官造成不可逆转的损害。镉污染还进一步造成了一定的致癌和非致癌健康风险。本研究总结了目前的镉污染状况、特定靶器官的毒性、致癌风险和一般人群的非致癌风险,以及膳食补充剂预防和减轻镉中毒的作用,旨在从个体和人群角度关注镉对人体的不良影响,希望不仅能降低镉中毒的健康风险,还能在未来更准确地预防和控制镉中毒。

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