College of Medicine, Shaoxing University, Shaoxing, China.
Shandong Public Security Bureau, Shandong, China.
Ann Hum Biol. 2021 Mar;48(2):157-159. doi: 10.1080/03014460.2021.1879264.
The Shandong Peninsula is the largest peninsula in China and has played a vital part in Chinese civilisation. The ancient independent Laizi kingdom was located on the Shandong peninsula. While large demographic changes have happened at this peninsula throughout history, the genetic landscape of modern populations on this peninsula has never been clarified. The aims of our study were to investigate population genetic characteristics of the populations on the Shandong peninsula and to reveal their genetic affinities with other populations around the world. Allele frequencies, Hardy-Weinberg equilibrium, and forensic parameters of 15 autosomal STRs in the AmpFSTR Identifiler system were obtained from the studied populations with 2441 individuals in total. Allele frequencies were used to reveal the phylogenetic relationships among 287 worldwide populations. The combined power of discrimination (CPD) and the combined power of exclusion (CPE) in the whole of the Han population on the Shandong Peninsula were 0.999999999999999983 and 0.999998155, respectively. The 15 autosomal loci were polymorphic and informative among our studied populations. Genetic homogeneities were revealed between the modern populations on the Shandong Peninsula and Han nationalities from Northeastern China as well as East China.
山东半岛是中国最大的半岛，在中国文明中发挥了重要作用。古代独立的莱子国位于山东半岛。虽然历史上这个半岛发生了大规模的人口变化，但这个半岛上现代人口的遗传景观从未被阐明。我们研究的目的是调查山东半岛人口的遗传特征，并揭示他们与世界其他地区人口的遗传亲缘关系。我们从总共 2441 名个体中获得了 AmpFSTR Identifiler 系统中 15 个常染色体 STR 的等位基因频率、哈迪-温伯格平衡和法医参数。等位基因频率用于揭示 287 个全球人群之间的系统发育关系。在整个山东半岛汉族人群中，综合判别能力（CPD）和综合排除能力（CPE）分别为 0.999999999999999983 和 0.999998155。这 15 个常染色体基因座在我们研究的人群中是多态的和信息丰富的。山东半岛和中国东北地区以及华东地区的现代人群与汉族之间存在遗传同质性。
