Nottingham Audiology Services, Nottingham University Hospitals Trust, Nottingham, UK.
NIHR Nottingham Biomedical Research Centre, University of Nottingham, Nottingham, UK.
J Laryngol Otol. 2021 Jan;135(1):14-20. doi: 10.1017/S0022215121000025. Epub 2021 Jan 25.
Platinum-based chemotherapy drugs are associated with substantial ototoxicity. The hearing of children treated with these drugs should be closely monitored.
A questionnaire was sent out to the 19 audiology departments associated with national paediatric cancer specialist centres in the UK looking at current practice in ototoxicity monitoring.
Responses were received from 17 of 19 centres (89 per cent). All offered some form of audiometric monitoring service. Extended high-frequency testing (9-20 kHz) was only utilised by 7 services (29 per cent). A majority of respondents were reluctant to consider self-test devices in paediatric ototoxicity monitoring (n = 9; 53 per cent). Provision of long-term audiological follow up is sporadic with only 4 (23 per cent) respondents keeping all children with normal hearing under review once treatment is completed.
While some good practice in paediatric ototoxicity was identified, opportunities exist to improve clinical practice and protocols, promote multidisciplinary team working and to utilise technologies such as extended high frequency and self-test audiometry.
铂类化疗药物与严重的耳毒性相关。接受这些药物治疗的儿童的听力应密切监测。
向英国 19 家与国家儿科癌症专科中心相关的听力学部门发出问卷，调查耳毒性监测的当前实践情况。
19 个中心中的 17 个（89%）做出了回应。所有中心都提供某种形式的听力监测服务。只有 7 个服务（29%）进行扩展高频测试（9-20 kHz）。大多数受访者不愿考虑在儿科耳毒性监测中使用自我测试设备（n=9；53%）。长期听力随访的提供是零星的，只有 4 个（23%）受访者在治疗完成后对所有听力正常的儿童进行审查。
虽然确定了一些儿科耳毒性方面的良好实践，但仍有机会改善临床实践和方案，促进多学科团队合作，并利用扩展高频和自我测试听力等技术。
